Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225538'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225538(GTC000242A)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F
Show InChI InChI=1S/C24H25FN8O/c1-3-32(21-7-4-6-20-18(21)13-27-30-20)23-19(25)14-26-24(29-23)28-16-8-9-17-15(2)31-33(10-5-11-34)22(17)12-16/h4,6-9,12-14,34H,3,5,10-11H2,1-2H3,(H,27,30)(H,26,28,29)
Affinity DataIC50: 1.58nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225538(GTC000242A)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F
Show InChI InChI=1S/C24H25FN8O/c1-3-32(21-7-4-6-20-18(21)13-27-30-20)23-19(25)14-26-24(29-23)28-16-8-9-17-15(2)31-33(10-5-11-34)22(17)12-16/h4,6-9,12-14,34H,3,5,10-11H2,1-2H3,(H,27,30)(H,26,28,29)
Affinity DataIC50: 2.77nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225538(GTC000242A)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F
Show InChI InChI=1S/C24H25FN8O/c1-3-32(21-7-4-6-20-18(21)13-27-30-20)23-19(25)14-26-24(29-23)28-16-8-9-17-15(2)31-33(10-5-11-34)22(17)12-16/h4,6-9,12-14,34H,3,5,10-11H2,1-2H3,(H,27,30)(H,26,28,29)
Affinity DataIC50: 3.61nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225538(GTC000242A)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F
Show InChI InChI=1S/C24H25FN8O/c1-3-32(21-7-4-6-20-18(21)13-27-30-20)23-19(25)14-26-24(29-23)28-16-8-9-17-15(2)31-33(10-5-11-34)22(17)12-16/h4,6-9,12-14,34H,3,5,10-11H2,1-2H3,(H,27,30)(H,26,28,29)
Affinity DataIC50: 3.88nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225538(GTC000242A)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F
Show InChI InChI=1S/C24H25FN8O/c1-3-32(21-7-4-6-20-18(21)13-27-30-20)23-19(25)14-26-24(29-23)28-16-8-9-17-15(2)31-33(10-5-11-34)22(17)12-16/h4,6-9,12-14,34H,3,5,10-11H2,1-2H3,(H,27,30)(H,26,28,29)
Affinity DataIC50: 9.62nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed