Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225545'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225545(GTC000249A)
Show SMILES CN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F
Show InChI InChI=1S/C19H16FN7O2S/c1-27(16-4-2-3-15-13(16)9-22-26-15)18-14(20)10-21-19(25-18)24-12-6-5-11-8-23-30(28,29)17(11)7-12/h2-7,9-10,23H,8H2,1H3,(H,22,26)(H,21,24,25)
Affinity DataIC50: 1.99nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sidPDB
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225545(GTC000249A)
Show SMILES CN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F
Show InChI InChI=1S/C19H16FN7O2S/c1-27(16-4-2-3-15-13(16)9-22-26-15)18-14(20)10-21-19(25-18)24-12-6-5-11-8-23-30(28,29)17(11)7-12/h2-7,9-10,23H,8H2,1H3,(H,22,26)(H,21,24,25)
Affinity DataIC50: 11.6nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sidPDB