Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225562'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 1.30nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 2.03nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 4.49nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 5.36nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 8.05nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 8.18nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 8.41nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 8.41nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 9.27nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 11.2nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 11.3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 13.1nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Show SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12
Show InChI InChI=1S/C22H21FN8O/c1-30-20-10-15(7-6-14(20)11-26-30)27-22-24-13-17(23)21(28-22)31(8-3-9-32)19-5-2-4-18-16(19)12-25-29-18/h2,4-7,10-13,32H,3,8-9H2,1H3,(H,25,29)(H,24,27,28)
Affinity DataIC50: 13.3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed