Report error Found 23 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM25045'
Affinity DataKd: 12nMAssay Description:Binding constant for MTOR kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) using Ulight-4E-BP1 as substrate incubated for 30 mins by fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of mTOR kinase (unknown origin) assessed as suppression of ULight-4E-BP1 substrate phosphorylation incubated for 1 hr by lance ultra assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of mTOR (unknown origin) using ATP as substrate after 60 mins by Lance ultra assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of mTOR (unknown origin) by lance ultra assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR kinase (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR (unknown origin) using ULight4E-BP1 peptide as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Competitive inhibition of human mTOR using 4EBP1 as substrate in presence of [33gammaP]-ATP after 120 mins by filter binding methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of mTOR (unknown origin) in the presence of ATP by TR-FRET-based LanthaScreen methodMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human mTOR (1362 to end residue) using ULight-4EBP1 peptide as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Inhibition of human mTOR/FRAP1 using 4EBP1 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of human mTORMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 as substrate measured after 45 mins in presence of ATP by LANCE Ultra assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nM ΔG°: -44.1kJ/mole IC50: 38nMT: 2°CAssay Description:The LanthaScreen TR-FRET mTOR assay was performed using Costar low-binding 284-well plates at room temperature according to the instructions of the m...More data for this Ligand-Target Pair
Affinity DataKi: 20nM IC50: 82nMAssay Description:The mTOR activity was determined by measuring the amount of [gamma-33 P] phosphae from ATP incorporated in the substrate protein.More data for this Ligand-Target Pair
