Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM35615'
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35615(pyrazolo pyrimidine, 5u)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35615(pyrazolo pyrimidine, 5u)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35615(pyrazolo pyrimidine, 5u)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35615(pyrazolo pyrimidine, 5u)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR (unknown origin) expressed in HEK293 cells assessed as decrease in phosphorylation of S6K level at Thr389 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed