Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Sigma intracellular receptor 2' and Ligand = 'BDBM349513'
TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  11nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  11nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  11nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  11nMAssay Description:Binding affinity to Sigma 2-receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  11nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent