Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Sigma intracellular receptor 2' and Ligand = 'BDBM349547'
TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  8nMAssay Description:Binding affinity to sigma2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  8.5nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity to Sigma 2-receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  8.5nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  8.5nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 349547BDBM349547(US10207991, Ex. Cpd. No. 62 | US10611728, Example ...)
Affinity DataKi:  8.5nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent