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Report error Found 9 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50062915'
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 24nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 83nMAssay Description:Displacement of [3H]WIN 35428 from Sprague-Dawley rat striatal tissue after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 83nMAssay Description:The compound was tested for its affinity at the rat striatal dopamine transporter by the displacement of [3H]WIN-35428More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 83nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]WIN-35428 Binding to the Dopamine Transporter in Rhesus (Macaca mulatta) orCynomolgus Monkey (Macaca fascicularis) Caudate-PutamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 156nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataKi:  125nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)