Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Steryl-sulfatase' and Ligand = 'BDBM50355372'
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataIC50: 220nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataIC50: 230nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataKi:  250nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataIC50: 310nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataIC50: 310nMAssay Description:Estrone-sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataIC50: 325nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355372BDBM50355372(CHEMBL482212)
Affinity DataIC50: 325nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed