Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with Target = 'Steryl-sulfatase' and Ligand = 'BDBM50366532'
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 8.30nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 12nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 12nMAssay Description:Inhibition of estrone sulfatase (unknown origin) transfected in HEK293 cells using [3H]E1S as substrate incubated for 2 hrs by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 13nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 14nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of steroid sulfatase in human JEG3 cells using [3H] E1S as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Estrone-sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366532BDBM50366532(CHEMBL518966)
Affinity DataIC50: 45nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed