Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Steryl-sulfatase' and Ligand = 'BDBM50369432'
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.0300nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human placental estrone sulfatase expressed in HEK293 cells using [3H]E1S as substrate incubated for 2 hrs by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 1.40nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Laval University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369432BDBM50369432(CHEMBL1627465)
Affinity DataIC50: 30nMAssay Description:Inhibition of estrone sulfatase in human JEG-3 cells using [3H]-estrone sulphate as substrate incubated for 1 hr by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed