Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50255227'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255227(CHEMBL450161 | N-(5-([1,2,4]triazolo[1,5-a]pyridin...)
Affinity DataKi:  2.95nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255227(CHEMBL450161 | N-(5-([1,2,4]triazolo[1,5-a]pyridin...)
Affinity DataEC50:  5.78E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255227(CHEMBL450161 | N-(5-([1,2,4]triazolo[1,5-a]pyridin...)
Affinity DataEC50:  165nMAssay Description:Inhibition of TGFBR1 (unknown origin) transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed