Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50304849'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304849(4-(3-ethylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304849(4-(3-ethylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataIC50:  390nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed