Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM100349'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100349(US10533001, Example Table 9a.2 | US11414410, Table...)
Affinity DataKd:  11nMAssay Description:ATP-site dependent competition binding assay using Ambit KinomeScan Screening kit.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100349(US10533001, Example Table 9a.2 | US11414410, Table...)
Affinity DataKd:  11nMAssay Description:The kinase reaction is performed in a black U-bottom 96-well microtitre plate. The final reaction volume is 50 μL and contains a final concentra...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100349(US10533001, Example Table 9a.2 | US11414410, Table...)
Affinity DataKd:  11nMAssay Description:Syk and JAK: The activity of a specified compound as an inhibitor of a JAK kinase may be assessed in vitro or in vivo. In some embodiments, the activ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM100349(US10533001, Example Table 9a.2 | US11414410, Table...)
Affinity DataKd:  11nMAssay Description:This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...More data for this Ligand-Target Pair
In DepthDetails US Patent