Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with Target = 'Urotensin-2 receptor' and Ligand = 'BDBM50302272'
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataIC50: 3.60nMAssay Description:Binding affinity to human urotensin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataKi:  5nMAssay Description:Binding affinity to human urotensin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat urotensin 2 receptor expressed in CHO cells assessed as calcium mobilization at 10000 nM by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at recombinant human urotensin2 receptor expressed in CHO cells assessed as inhibition of urotensin2-stimulated Ca2+ mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at rat urotensin 2 receptor expressed in CHO cells assessed as calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Cat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to cat urotensin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataKi:  1.48E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302272BDBM50302272(ACT-058362 | CHEMBL1164032 | CHEMBL567303 | 1-(2-(...)
Affinity DataIC50: 7.50E+4nMAssay Description:Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed