Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM5364'
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5364BDBM5364(N,5-diphenyl-1,3-oxazol-2-amine | 2-Anilino-5-aryl...)
Affinity DataIC50: 134nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 5364BDBM5364(N,5-diphenyl-1,3-oxazol-2-amine | 2-Anilino-5-aryl...)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2005
Entry Details Article
PubMed