Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Vitamin D3 receptor' and Ligand = 'BDBM50030475'
TargetVitamin D3 receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030475(CHEBI:28940 | 7-Dehydrocholesterol | Cholecalcifer...)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030475(CHEBI:28940 | 7-Dehydrocholesterol | Cholecalcifer...)
Affinity DataIC50: 87nMAssay Description:Agonist activity at Vitamin D receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetVitamin D3 receptor(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50030475(CHEBI:28940 | 7-Dehydrocholesterol | Cholecalcifer...)
Affinity DataEC50:  900nMAssay Description:Activation of VDR in mouse ASZ001 cells assessed as change in Cyp24A1 mRNA expression after 48 hrs by q-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed