Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Vitamin D3 receptor' and Ligand = 'BDBM50565949'
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataEC50:  0.0140nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at human VDR expressed in African green monkey COS7 cells expressing mouse osteopontin VDRE assessed as induction of receptor transa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataEC50:  36nMAssay Description:Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reductio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Bovine)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]-1-alpha,25-(OH)2D3 from bovine thymus VDR incubated for 18 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed