Compile Data Set for Download or QSAR
Report error Found 58 of Enz. Inhib. data with enzyme = '5-hydroxytryptamine receptor 2A' and Substrate = 'BDBM21395'
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35255BDBM35255(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
Affinity DataKi:  0.5nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35256BDBM35256(MIANSERIN (+) | MIANSERIN | Lerivon | Tolvon | MIA...)
Affinity DataKi:  3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21395BDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi:  3.5nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35254BDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  4nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35927BDBM35927([3-(9,10-Dihydro-anthracen-9-yl)-propyl]-methyl-am...)
Affinity DataKi:  13nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35245BDBM35245(3-(phenylsulfonyl)-1H-indole, 18g)
Affinity DataKi:  19nM IC50: 31nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35920BDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35928BDBM35928(CHEMBL346230 | 3-(9,10-dihydroanthracen-9-yl)-N,N-...)
Affinity DataKi:  22nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35926BDBM35926(3-(9,10-Dihydro-anthracen-9-yl)-propylamine | CHEM...)
Affinity DataKi:  32nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35248BDBM35248(3-(phenylsulfonyl)-1H-indole, 18j)
Affinity DataKi:  33nM IC50: 69nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35250BDBM35250(3-(phenylsulfonyl)-1H-indole, 18l)
Affinity DataKi:  46nM IC50: 57nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35921BDBM35921(1-(9,10-dihydroanthracen-9-yl)-N-methylmethanamine...)
Affinity DataKi:  52nM ΔG°:  -9.86kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35247BDBM35247(3-(phenylsulfonyl)-1H-indole, 18i)
Affinity DataKi:  59nM IC50: 180nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21372BDBM21372(CHEMBL222188 | 6-(4-phenylpiperazin-1-yl)-N-(1,2,3...)
Affinity DataKi:  77.8nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35925BDBM35925(9,10-dihydroanthracene(DHA), 2c)
Affinity DataKi:  84nM ΔG°:  -9.58kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35249BDBM35249(3-(phenylsulfonyl)-1H-indole, 18k)
Affinity DataKi:  89nM IC50: 92nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35924BDBM35924(9,10-dihydroanthracene(DHA), 2b)
Affinity DataKi:  92nM ΔG°:  -9.53kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35244BDBM35244(3-(phenylsulfonyl)-1H-indole, 18f)
Affinity DataKi:  110nM IC50: 650nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35246BDBM35246(3-(phenylsulfonyl)-1H-indole, 18h)
Affinity DataKi:  117nM IC50: 258nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21389BDBM21389(6-[4-(2-fluorophenyl)piperazin-1-yl]-N-(1,2,3,4-te...)
Affinity DataKi:  194nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35232BDBM35232(3-(phenylsulfonyl)-1H-indole, 18b)
Affinity DataKi:  222nM IC50: 832nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35231BDBM35231(3-(phenylsulfonyl)-1H-indole, 18a)
Affinity DataKi:  262nM IC50: 459nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21369BDBM21369(CHEMBL222755 | 6-[4-(2-methylphenyl)piperazin-1-yl...)
Affinity DataKi:  262nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35241BDBM35241(3-(phenylsulfonyl)-1H-indole, 18c)
Affinity DataKi:  273nM IC50: 1.11E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21373BDBM21373(6-[4-(2-nitrophenyl)piperazin-1-yl]-N-(1,2,3,4-tet...)
Affinity DataKi:  282nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21374BDBM21374(CHEMBL222477 | 6-[4-(2-chlorophenyl)piperazin-1-yl...)
Affinity DataKi:  301nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  326nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35243BDBM35243(3-(phenylsulfonyl)-1H-indole, 18e)
Affinity DataKi:  367nM IC50: 1.08E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35242BDBM35242(3-(phenylsulfonyl)-1H-indole, 18d)
Affinity DataKi:  389nM IC50: 1.03E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35251BDBM35251(3-(phenylsulfonyl)-1H-indole, 33a)
Affinity DataKi:  713nM IC50: 477nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35923BDBM35923(9-(2-aminoethyl)-9,10-dihydroanthracene | 2-(9,10-...)
Affinity DataKi:  480nM ΔG°:  -8.56kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21390BDBM21390(6-[4-(pyridin-2-yl)piperazin-1-yl]-N-(1,2,3,4-tetr...)
Affinity DataKi:  535nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35922BDBM35922(CHEMBL160933 | 1-(9,10-dihydroanthracen-9-yl)-N,N-...)
Affinity DataKi:  540nM ΔG°:  -8.49kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21384BDBM21384(6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1...)
Affinity DataKi:  559nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35252BDBM35252(3-(phenylsulfonyl)-1H-indole, 33b)
Affinity DataKi:  619nM IC50: 5.98E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21375BDBM21375(6-[4-(2-cyanophenyl)piperazin-1-yl]-N-(1,2,3,4-tet...)
Affinity DataKi:  700nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35936BDBM35936(diphenylalkylamine (DPA), 6b)
Affinity DataKi:  754nM ΔG°:  -8.29kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35253BDBM35253(3-(phenylsulfonyl)-1H-indole, 33c)
Affinity DataKi:  854nM IC50: 7.97E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35937BDBM35937(diphenylalkylamine (DPA), 6c)
Affinity DataKi:  1.15E+3nM ΔG°:  -8.04kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21368BDBM21368(CHEMBL224820 | 6-[4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  1.26E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21383BDBM21383(6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-te...)
Affinity DataKi:  1.46E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35933BDBM35933(diphenylalkylamine (DPA), 5b)
Affinity DataKi:  1.50E+3nM ΔG°:  -7.89kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21385BDBM21385(6-{4-[2-(methylamino)phenyl]piperazin-1-yl}-N-(1,2...)
Affinity DataKi:  1.59E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35934BDBM35934(diphenylalkylamine (DPA), 5c)
Affinity DataKi:  1.64E+3nM ΔG°:  -7.84kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35935BDBM35935(diphenylalkylamine (DPA), 6a)
Affinity DataKi:  2.59E+3nM ΔG°:  -7.57kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21379BDBM21379(6-[4-(2-propylphenyl)piperazin-1-yl]-N-(1,2,3,4-te...)
Affinity DataKi:  3.19E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21378BDBM21378(6-[4-(2-ethylphenyl)piperazin-1-yl]-N-(1,2,3,4-tet...)
Affinity DataKi:  3.37E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21371BDBM21371(CHEMBL225512 | 6-[4-(2-hydroxyphenyl)piperazin-1-y...)
Affinity DataKi:  3.39E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21387BDBM21387(6-[4-(2-acetamidophenyl)piperazin-1-yl]-N-(1,2,3,4...)
Affinity DataKi:  3.52E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universita Degli Studi Di Bari

LigandChemical structure of BindingDB Monomer ID 21376BDBM21376(2-{4-[5-(1,2,3,4-tetrahydronaphthalen-1-ylcarbamoy...)
Affinity DataKi: >4.00E+3nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Displayed 1 to 50 (of 58 total ) | Next | Last >>
Jump to: