Compile Data Set for Download or QSAR
Report error Found 893 of Enz. Inhib. data with enzyme = 'Acetylcholinesterase' and Substrate = 'BDBM8959'
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9012BDBM9012(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 0.00800nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9022BDBM9022(N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.0200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10597BDBM10597((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Affinity DataKi:  0.0260nM ΔG°:  -14.4kcal/molepH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by E llman. Inhibition of enzyme activity was measured over a substrate c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9017BDBM9017(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 0.0400nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 8965BDBM8965(CHEMBL338755 | methylbis[3-(1,2,3,4-tetrahydroacri...)
Affinity DataKi:  0.0600nM ΔG°:  -13.9kcal/molepH: 8.0 T: 2°CAssay Description:Inhibition of enzyme activity was measured over a substrate concentration range of 0.01-30 mM and at least six inhibitor concentrations to determine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9023BDBM9023(N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)ami...)
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 9054BDBM9054(6-chloro-N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.0700nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9009BDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 0.100nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9035BDBM9035(N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)ami...)
Affinity DataIC50: 0.200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9009BDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 0.200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 8963BDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10512BDBM10512(CHEMBL194823 | N-{3-[(6-chloro-1,2,3,4-tetrahydroa...)
Affinity DataKi:  155nM ΔG°:  -9.66kcal/mole IC50: 0.253nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10590BDBM10590({3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino...)
Affinity DataIC50: 0.290nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10692BDBM10692(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10692BDBM10692(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 9055BDBM9055(6-chloro-N-{8-[(6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9037BDBM9037(N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.300nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Tsukuba Research Laboratories

LigandChemical structure of BindingDB Monomer ID 9410BDBM9410(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-ethyl-4-(phe...)
Affinity DataIC50: 0.300nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10693BDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10693BDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10586BDBM10586([3-({7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^...)
Affinity DataIC50: 0.320nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10585BDBM10585(7-chloro-15-methyl-N-[8-(1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.330nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10588BDBM10588(CHEMBL2011492 | 3-Chloro-6,7,10,11-tetrahydro-9-me...)
Affinity DataIC50: 0.330nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10584BDBM10584(7-chloro-15-methyl-N-[7-(1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.340nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10589BDBM10589(CHEMBL2011496 | 3-Chloro-6,7,10,11-tetrahydro-9-me...)
Affinity DataIC50: 0.400nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10587BDBM10587(7-chloro-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.450nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9018BDBM9018(N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-6-(1,2,3,4-te...)
Affinity DataIC50: 0.450nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10583BDBM10583(CHEMBL2011483 | 7-chloro-15-methyl-N-[6-(1,2,3,4-t...)
Affinity DataIC50: 0.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9007BDBM9007(7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic...)
Affinity DataIC50: 0.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9038BDBM9038(N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9024BDBM9024(N-[8-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10697BDBM10697(3-{[methyl(7-{[(2Z)-3-oxo-2-(3,4,5-trimethoxybenzy...)
Affinity DataIC50: 0.520nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10932BDBM10932(3-{[ethyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})a...)
Affinity DataIC50: 0.560nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 9051BDBM9051(6-fluoro-N-{7-[(6-fluoro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 9053BDBM9053(6-chloro-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9036BDBM9036(2-(5-bromo-1H-indol-3-yl)-N-{7-[(6-chloro-1,2,3,4-...)
Affinity DataIC50: 0.600nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Tsukuba Research Laboratories

LigandChemical structure of BindingDB Monomer ID 9409BDBM9409(N-[2-(1-benzylpiperidin-4-yl)ethyl]-N-methyl-4-(ph...)
Affinity DataIC50: 0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Tsukuba Research Laboratories

LigandChemical structure of BindingDB Monomer ID 9411BDBM9411(CHEMBL54058 | N-[2-(1-benzylpiperidin-4-yl)ethyl]-...)
Affinity DataIC50: 0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The amount of a yellow substance formed after incubation was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 8968BDBM8968(2-{bis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)prop...)
Affinity DataKi:  0.650nM ΔG°:  -12.5kcal/molepH: 8.0 T: 2°CAssay Description:Inhibition of enzyme activity was measured over a substrate concentration range of 0.01-30 mM and at least six inhibitor concentrations to determine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9014BDBM9014(N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...)
Affinity DataIC50: 0.650nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9029BDBM9029(N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.700nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 9052BDBM9052(6-fluoro-N-{8-[(6-fluoro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10938BDBM10938(3-[({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl}(propan-...)
Affinity DataIC50: 0.700nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandChemical structure of BindingDB Monomer ID 9042BDBM9042(2-(1H-indol-3-yl)ethyl N-{6-[(6-chloro-1,2,3,4-tet...)
Affinity DataIC50: 0.700nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandChemical structure of BindingDB Monomer ID 10469BDBM10469(CHEMBL424707 | Bis-THA inhibitor 8 | N-[9-(1,2,3,4...)
Affinity DataIC50: 0.770nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10592BDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 0.780nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Weizmann Institute of Science

LigandChemical structure of BindingDB Monomer ID 10439BDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  0.800nM ΔG°:  -12.3kcal/mole IC50: 2.40nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10913BDBM10913(3-{[methyl({5-[(9-oxo-9H-xanthen-3-yl)oxy]pentyl})...)
Affinity DataIC50: 0.820nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 10582BDBM10582(15-ethyl-N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50: 0.820nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

LigandChemical structure of BindingDB Monomer ID 9010BDBM9010(6-[(8-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]...)
Affinity DataIC50: 0.870nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
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