Compile Data Set for Download or QSAR
Report error Found 7 of Enz. Inhib. data with enzyme = 'Activin receptor type-1' and Substrate = 'poly(Glu4, Tyr)'
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 36356BDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)
Affinity DataIC50: 26.7nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 50262079BDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 40.7nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 36355BDBM36355(DMH2 | 4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]py...)
Affinity DataIC50: 42.8nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 36354BDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 108nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 50262685BDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 148nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 5410BDBM5410(4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phe...)
Affinity DataIC50: 3.56E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Vanderbilt University

LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.53E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed