Compile Data Set for Download or QSAR
Report error Found 59 of Enz. Inhib. data with enzyme = 'Adenosine deaminase' and Substrate = 'BDBM14487'
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22925(Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...)
Affinity DataKi:  0.0330nM ΔG°:  -14.1kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22947(1-[(2R)-4-{5-[3-(4-chlorophenyl)propoxy]-1-methyl-...)
Affinity DataKi:  4.90nM ΔG°:  -11.2kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22937(1-[(2R)-4-{6-[(benzylcarbamoyl)amino]-1H-indol-1-y...)
Affinity DataKi:  7.5nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22920(1-[(2R)-1-hydroxy-4-{6-[3-(1-methyl-1H-1,3-benzodi...)
Affinity DataKi:  7.70nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22920(1-[(2R)-1-hydroxy-4-{6-[3-(1-methyl-1H-1,3-benzodi...)
Affinity DataKi:  7.70nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22920(1-[(2R)-1-hydroxy-4-{6-[3-(1-methyl-1H-1,3-benzodi...)
Affinity DataKi:  7.70nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22950(1-[(3R,4S)-4-hydroxy-1-(naphthalen-2-yloxy)pentan-...)
Affinity DataKi:  9.80nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22931(1-[(2R)-1-hydroxy-4-[6-(5-phenylpentanamido)-1H-in...)
Affinity DataKi:  11nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22948(CHEMBL93560 | 1-[(3R,4S)-4-hydroxy-1-(naphthalen-1...)
Affinity DataKi:  11nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22939(1-[(2R)-1-hydroxy-4-[6-(4-phenylbutoxy)-1H-indol-1...)
Affinity DataKi:  12nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22942(1-[(2R)-4-{6-[3-(4-chlorophenyl)propoxy]-1H-indol-...)
Affinity DataKi:  13nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22946(1-[(2R)-4-[5-(hexyloxy)-1-methyl-1H-indol-3-yl]-1-...)
Affinity DataKi:  13nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22949(1-[(3R,4S)-1-(2,3-dichlorophenyl)-4-hydroxypentan-...)
Affinity DataKi:  13nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22930(1-[(2R)-1-hydroxy-4-[6-(4-phenylbutanamido)-1H-ind...)
Affinity DataKi:  16nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22938(1-[(2R)-1-hydroxy-4-[6-(3-phenylpropoxy)-1H-indol-...)
Affinity DataKi:  17nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22936(1-[(2R)-1-hydroxy-4-{6-[3-(pyridin-3-yl)propanamid...)
Affinity DataKi:  17nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22928(1-[(2R)-4-(6-hexanamido-1H-indol-1-yl)-1-hydroxybu...)
Affinity DataKi:  24nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22945(1-[(2R)-1-hydroxy-4-[1-methyl-5-(3-phenylpropoxy)-...)
Affinity DataKi:  26nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22929(1-[(2R)-1-hydroxy-4-[6-(3-phenylpropanamido)-1H-in...)
Affinity DataKi:  30nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22935(1-[(2R)-1-hydroxy-4-{6-[4-(4-methylphenyl)butanami...)
Affinity DataKi:  34nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22926(3-(6-amino-9H-purin-9-yl)nonan-2-ol | Erythro-9-(2...)
Affinity DataKi:  37nM ΔG°:  -10.0kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22933(1-[(2R)-1-hydroxy-4-{6-[3-(4-methylphenyl)propanam...)
Affinity DataKi:  38nM ΔG°:  -10.0kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22940(1-[(2R)-4-[6-(hexyloxy)-1H-indol-1-yl]-1-hydroxybu...)
Affinity DataKi:  55nM ΔG°:  -9.80kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22934(1-[(2R)-1-hydroxy-4-{6-[3-(4-methoxyphenyl)propana...)
Affinity DataKi:  57nM ΔG°:  -9.78kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22932(1-[(2R)-1-hydroxy-4-[6-(6-phenylhexanamido)-1H-ind...)
Affinity DataKi:  91nM ΔG°:  -9.50kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28388(3-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-2-y...)
Affinity DataKi:  160nM ΔG°:  -9.42kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22941(1-[(2R)-4-(6-butoxy-1H-indol-1-yl)-1-hydroxybutan-...)
Affinity DataKi:  240nM ΔG°:  -8.93kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28383(N-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-2-y...)
Affinity DataKi:  510nM ΔG°:  -8.72kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22919(CHEMBL327830 | imidazole-4-carboxamide derivative,...)
Affinity DataKi:  680nM ΔG°:  -8.32kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28382(4-fluoro-N-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyri...)
Affinity DataKi:  960nM ΔG°:  -8.34kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28393((2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | CHEM...)
Affinity DataKi:  1.14E+3nM ΔG°:  -8.24kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28387(1-(4-fluorophenyl)-3-[4-({4-oxo-2H,4H,5H-pyrazolo[...)
Affinity DataKi:  1.15E+3nM ΔG°:  -8.23kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22918(2-(4-{5-[(1H-1,3-benzodiazol-2-ylamino)methyl]thio...)
Affinity DataKi:  1.20E+3nM ΔG°:  -7.99kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22927(1-[(2R)-4-(6-acetamido-1H-indol-1-yl)-1-hydroxybut...)
Affinity DataKi:  1.30E+3nM ΔG°:  -7.94kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22943(1-[(2R)-1-hydroxy-4-[5-(3-phenylpropoxy)-1H-indol-...)
Affinity DataKi:  1.90E+3nM ΔG°:  -7.72kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28389(1-[4-(dimethylamino)phenyl]-3-[4-({4-oxo-2H,4H,5H-...)
Affinity DataKi:  2.01E+3nM ΔG°:  -7.90kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28385(3-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-2-y...)
Affinity DataKi:  2.42E+3nM ΔG°:  -7.78kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22917(1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-ca...)
Affinity DataKi:  5.90E+3nM ΔG°:  -7.06kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22917(1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-ca...)
Affinity DataKi:  5.90E+3nM ΔG°:  -7.06kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22944(1-[(2R)-4-[5-(hexyloxy)-1H-indol-1-yl]-1-hydroxybu...)
Affinity DataKi:  6.20E+3nM ΔG°:  -7.03kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM21955(4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxym...)
Affinity DataKi:  1.06E+4nM ΔG°:  -6.78kcal/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM21953(4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)o...)
Affinity DataKi:  1.21E+4nM ΔG°:  -6.70kcal/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28380(N-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-2-y...)
Affinity DataKi:  1.27E+4nM ΔG°:  -6.79kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28381(4-methoxy-N-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyr...)
Affinity DataKi:  1.56E+4nM ΔG°:  -6.66kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM21957(N'-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxy...)
Affinity DataKi:  2.65E+4nM ΔG°:  -6.24kcal/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28386(1-(4-methoxyphenyl)-3-[4-({4-oxo-2H,4H,5H-pyrazolo...)
Affinity DataKi:  2.83E+4nM ΔG°:  -6.31kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28384(N-[4-({4-oxo-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-2-y...)
Affinity DataKi:  4.79E+4nM ΔG°:  -5.99kcal/molepH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM21956(7-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxym...)
Affinity DataKi:  5.14E+4nM ΔG°:  -5.85kcal/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM21954(7-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)o...)
Affinity DataKi:  5.20E+4nM ΔG°:  -5.84kcal/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22921(1-(2-hydroxy-1-phenylethyl)-1H-imidazole-4-carboxa...)
Affinity DataKi:  5.40E+4nM ΔG°:  -5.76kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
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