Compile Data Set for Download or QSAR
Report error Found 36 of Enz. Inhib. data with enzyme = 'Angiotensin-converting enzyme 2' and Substrate = 'BDBM21453'
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21489(MLN4760 | (2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichl...)
Affinity DataIC50: 0.440nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21488((2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dimethylphenyl)...)
Affinity DataIC50: 1.40nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21486((2S)-2-{[(1S)-1-carboxy-2-{1-[(3-methylphenyl)meth...)
Affinity DataIC50: 4.20nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21491((2S)-2-{[(1S)-1-carboxy-2-[1-(2-cyclohexylpropan-2...)
Affinity DataIC50: 10nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21487((2S)-2-{[(1S)-1-carboxy-2-{1-[(3,4-dimethylphenyl)...)
Affinity DataIC50: 10nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21482((2S)-2-{[(1S)-1-carboxy-2-{1-[(4-chlorophenyl)meth...)
Affinity DataIC50: 21nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21484((2S)-2-{[(1S)-1-carboxy-2-{1-[(4-methylphenyl)meth...)
Affinity DataIC50: 32nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21483((2S)-2-{[(1S)-1-carboxy-2-(1-{[4-(trifluoromethoxy...)
Affinity DataIC50: 52nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21481((2S)-2-{[(1S)-1-carboxy-2-{1-[(4-nitrophenyl)methy...)
Affinity DataIC50: 76nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21480((2S)-2-{[(1S)-1-carboxy-2-[1-(cyclohexylmethyl)-1H...)
Affinity DataIC50: 270nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21485((2S)-2-{[(1S)-1-carboxy-2-{1-[(2-methylphenyl)meth...)
Affinity DataIC50: 290nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21478((2S)-2-{[(1S)-2-(1-benzyl-1H-imidazol-5-yl)-1-carb...)
Affinity DataIC50: 300nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21479((2S)-2-{[(1S)-2-(1-benzyl-1H-imidazol-5-yl)-1-carb...)
Affinity DataIC50: 340nMpH: 6.5 T: 2°CAssay Description:Enzyme assay was conducted in 384-well microplates format. Activity was monitored by measuring increase in fluorescence (excitation @320 nm, emission...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21464(The second fraction of the HPLC chromatogram. | 2-...)
Affinity DataKi:  0.130nM ΔG°:  -13.5kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21474(3-({1-[2-acetamido-3-(1H-imidazol-4-yl)propanoyl]p...)
Affinity DataKi:  0.400nM ΔG°:  -12.8kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21470(The second fraction of the HPLC chromatogram. | 2-...)
Affinity DataKi:  0.700nM ΔG°:  -12.5kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21473(3-{[1-(2-acetamido-4-methylpentanoyl)pyrrolidin-2-...)
Affinity DataKi:  1.25nM ΔG°:  -12.1kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21467(2-benzyl-3-({1-[2-acetamido-3-(4-hydroxyphenyl)pro...)
Affinity DataKi:  5.20nM ΔG°:  -11.3kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21468(2-benzyl-3-{[1-(2-acetamido-3-phenylpropanoyl)pyrr...)
Affinity DataKi:  5.20nM ΔG°:  -11.3kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21465(3-{[1-(6-amino-2-acetamidohexanoyl)pyrrolidin-2-yl...)
Affinity DataKi:  6.5nM ΔG°:  -11.2kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21469(2-benzyl-3-{[1-(2-acetamido-3-methylbutanoyl)pyrro...)
Affinity DataKi:  6.60nM ΔG°:  -11.2kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21466(5-{2-[(2-benzyl-2-carboxyethyl)(hydroxy)phosphoryl...)
Affinity DataKi:  7nM ΔG°:  -11.1kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21463(2-benzyl-3-{[1-(2-acetamidopropanoyl)pyrrolidin-2-...)
Affinity DataKi:  7.5nM ΔG°:  -11.1kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21475(3-({1-[2-acetamido-3-(1H-imidazol-4-yl)propanamido...)
Affinity DataKi:  220nM ΔG°:  -9.08kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21454(2-[({1-[(benzyloxy)carbonyl]pyrrolidin-2-yl}(hydro...)
Affinity DataKi:  300nM ΔG°:  -8.89kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21452(2-benzyl-3-({1-[(benzyloxy)carbonyl]pyrrolidin-2-y...)
Affinity DataKi:  300nM ΔG°:  -8.89kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21472(2-benzyl-3-({1-[2-acetamido-3-(1H-imidazol-4-yl)pr...)
Affinity DataKi:  800nM ΔG°:  -8.31kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21471(2-benzyl-3-{[1-(2-acetamido-4-methylpentanamido)-2...)
Affinity DataKi:  920nM ΔG°:  -8.23kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21455(3-({1-[(benzyloxy)carbonyl]pyrrolidin-2-yl}(hydrox...)
Affinity DataKi:  3.00E+3nM ΔG°:  -7.53kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21458(2-benzyl-3-[(1-{[(benzyloxy)carbonyl]amino}-3-meth...)
Affinity DataKi:  8.00E+3nM ΔG°:  -6.95kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21461(CHEMBL36716 | 3-[(1-amino-3-methylbutyl)(hydroxy)p...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21460(CHEMBL34068 | 3-[(1-amino-2-phenylethyl)(hydroxy)p...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21459(CHEMBL51566 | 3-[(1-aminoethyl)(hydroxy)phosphoryl...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21462(2-benzyl-3-[hydroxy(pyrrolidin-2-yl)phosphoryl]pro...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21457(2-benzyl-3-[(1-{[(benzyloxy)carbonyl]amino}-2-phen...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Millennium Pharmaceuticals

LigandPNGBDBM21456(2-benzyl-3-[(1-{[(benzyloxy)carbonyl]amino}ethyl)(...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed