Compile Data Set for Download or QSAR
Report error Found 26 of Enz. Inhib. data with enzyme = 'Aurora kinase A' and Substrate = 'FAM-PKAtide'
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26333(1-[3-(pyrrolidin-1-ylmethyl)-5-(trifluoromethyl)ph...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26326(1-(3-chlorophenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26322(1-(3-methylphenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26330(1-(3-chloro-4-fluorophenyl)-3-[5-(2-{thieno[3,2-d]...)
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26315(3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: 22nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26325(1-(3-fluorophenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50: 23nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26331(1-1H-indol-7-yl-3-[5-(2-{thieno[3,2-d]pyrimidin-4-...)
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26327(1-(4-chlorophenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50: 39nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26324(1-(3-ethynylphenyl)-3-[5-(2-{thieno[3,2-d]pyrimidi...)
Affinity DataIC50: 41nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26323(1-(3-methoxyphenyl)-3-[5-(2-{thieno[3,2-d]pyrimidi...)
Affinity DataIC50: 50nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26320(1-phenyl-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino...)
Affinity DataIC50: 52nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26334(1-{3-[2-(azetidin-1-yl)ethyl]phenyl}-3-[5-(2-{thie...)
Affinity DataIC50: 53nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26329(1-(3,4-dichlorophenyl)-3-[5-(2-{thieno[3,2-d]pyrim...)
Affinity DataIC50: 96nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26314(CHEMBL518666 | 3-[1-(2-{thieno[3,2-d]pyrimidin-4-y...)
Affinity DataIC50: 250nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26332(1-cyclohexyl-3-[5-(2-{thieno[3,2-d]pyrimidin-4-yla...)
Affinity DataIC50: 270nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26328(1-(2-chlorophenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50: 280nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26313(3-[1-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: 1.20E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26311(CHEMBL461999 | 3-[4-(2-{thieno[3,2-d]pyrimidin-4-y...)
Affinity DataIC50: 1.20E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26317(N-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: 2.50E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26309(N-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)ph...)
Affinity DataIC50: 3.20E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26319(2-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: 4.90E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26321(1-methyl-1-phenyl-3-[5-(2-{thieno[3,2-d]pyrimidin-...)
Affinity DataIC50: 7.20E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26318(N-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26316(CHEMBL513076 | 3-[4-(2-{thieno[3,2-d]pyrimidin-4-y...)
Affinity DataIC50: 2.00E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26312(3-[3-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)ph...)
Affinity DataIC50: 2.00E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26310(CHEMBL461995 | 4-(2-{thieno[3,2-d]pyrimidin-4-ylam...)
Affinity DataIC50: 2.00E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed