Compile Data Set for Download or QSAR
Report error Found 13 of Enz. Inhib. data with enzyme = 'Aurora kinase B' and Substrate = 'Biotinylated Cross-tide Substrate'
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27083BDBM27083(1-(2,6-difluorophenyl)-3-{3-[5-(morpholin-4-ylmeth...)
Affinity DataIC50: 2.60nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27084BDBM27084(1-cyclohexyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-1,3...)
Affinity DataIC50: 5.20nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27086BDBM27086(3-{3-[5-(morpholin-4-ylmethyl)-1H-1,3-benzodiazol-...)
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27082BDBM27082(1-(2-fluorophenyl)-3-{3-[5-(morpholin-4-ylmethyl)-...)
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27079BDBM27079(N-{3-[5-(morpholin-4-ylmethyl)-1H-1,3-benzodiazol-...)
Affinity DataIC50: 15nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataIC50: 17nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27085BDBM27085(3-{3-[5-(morpholin-4-ylmethyl)-1H-1,3-benzodiazol-...)
Affinity DataIC50: 24nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27081BDBM27081(3-{3-[5-(morpholin-4-ylmethyl)-1H-1,3-benzodiazol-...)
Affinity DataIC50: 54nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27080BDBM27080(4-fluoro-N-{3-[5-(morpholin-4-ylmethyl)-1H-1,3-ben...)
Affinity DataIC50: 75nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27078BDBM27078(N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]ben...)
Affinity DataIC50: 180nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27077BDBM27077(N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]ace...)
Affinity DataIC50: 510nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 24637BDBM24637(2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole | JMC52379...)
Affinity DataIC50: 6.50E+3nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astex Therapeutics

LigandChemical structure of BindingDB Monomer ID 27087BDBM27087(3-cyclopropyl-1-{3-[5-(morpholin-4-ylmethyl)-1H-1,...)
Affinity DatapH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed