Compile Data Set for Download or QSAR
Report error Found 37 of Enz. Inhib. data with enzyme = 'Aurora kinase B' and Substrate = 'Biotinylated Peptide Substrate'
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26297(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[ethyl(2-hydrox...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26298(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethy...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26299(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26301(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(p...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26302(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26303(N-(2,3-difluorophenyl)-2-{4-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26304(N-(2,3-difluorophenyl)-2-{4-[(7-{3-[ethyl(2-hydrox...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26305(N-(3-fluorophenyl)-2-{4-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26306(2-{4-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26307(N-(3-fluorophenyl)-2-{4-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26308(N-(2,3-difluorophenyl)-2-{4-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26277(N-(3,5-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26284(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26285(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2S)-2-(hydrox...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26286(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26287(N-(2,3-difluorophenyl)-2-[3-({7-[3-(4-hydroxypiper...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26288(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26289(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26290(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)am...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26291(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(m...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26292(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26294(CHEMBL214848 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26295(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethy...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26296(CHEMBL216053 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26274(N-(3-fluorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26276(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26293(CHEMBL217804 | N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26278(N-(3-chlorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26282(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  9nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26283(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  13nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26273(N-(2-fluorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  14nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26272(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  18nM ΔG°:  -10.5kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26275(N-(4-fluorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  30nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26280(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  39nM ΔG°:  -10.0kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26279(N-(3-cyanophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)pi...)
Affinity DataKi:  83nM ΔG°:  -9.56kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Astrazeneca

LigandPNGBDBM26281(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  140nM ΔG°:  -9.25kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed