Compile Data Set for Download or QSAR
Report error Found 10 of Enz. Inhib. data with enzyme = 'Aurora kinase B' and Substrate = 'Histone H3'
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24722BDBM24722(7,7,16-trimethyl-5,11,14,15-tetraazapentacyclo[10....)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24721BDBM24721(5-ethyl-7,7,16-trimethyl-5,11,14,15-tetraazapentac...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24720BDBM24720(5-methyl-3,4,17-triazatetracyclo[8.7.0.0^{2,6}.0^{...)
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24723BDBM24723(5,5,16-trimethyl-7,11,14,15-tetraazapentacyclo[10....)
Affinity DataIC50: 86nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24712BDBM24712(5-ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-...)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24711BDBM24711(7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H...)
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24714BDBM24714(5-methyl-3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{...)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24718BDBM24718(2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole | pyrazole-...)
Affinity DataIC50: 510nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandChemical structure of BindingDB Monomer ID 24719BDBM24719(13-methyl-8,11,12-triazatetracyclo[7.6.0.0^{2,7}.0...)
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed