Compile Data Set for Download or QSAR
Report error Found 29 of Enz. Inhib. data with enzyme = 'Bcl-2-like protein 1' and Substrate = 'Bak-BH3 peptide'
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31809(Apogossypol derivative, 8k)
Affinity DataIC50: 270nM Kd:  110nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31810(Apogossypol derivative, 8r)
Affinity DataIC50: 760nM Kd:  110nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31808(Apogossypol derivative, 8j)
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31805(Apogossypol derivative, 8n)
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31811(Apogossypol derivative, 8s)
Affinity DataIC50: 850nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31807(Apogossypol derivative, 8q)
Affinity DataIC50: 930nM Kd:  120nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31804(Apogossypol derivative, 8m)
Affinity DataIC50: 1.10E+3nM Kd:  850nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25537(4-(2-hydroxyethyl)-8-methyl-12,14-dioxa-8-azatetra...)
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31803(Apogossypol derivative, 12e)
Affinity DataIC50: 3.50E+3nM Kd:  410nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31802(Apogossypol | US9115061, Apogossypol)
Affinity DataIC50: 3.70E+3nM Kd:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25539(4-(2-methoxyethyl)-8-methyl-12,14-dioxa-8-azatetra...)
Affinity DataIC50: 6.00E+3nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM31806(Apogossypol derivative, 8p)
Affinity DataIC50: 6.30E+3nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25538(4-(methoxymethyl)-8-methyl-12,14-dioxa-8-azatetrac...)
Affinity DataIC50: 1.10E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25536(4-(hydroxymethyl)-8-methyl-12,14-dioxa-8-azatetrac...)
Affinity DataIC50: 1.10E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25530(8-methyl-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}...)
Affinity DataIC50: 1.20E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25540(7,8-dihydroxy-5-methylphenanthridin-5-ium chloride...)
Affinity DataIC50: 1.80E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataIC50: 1.90E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25541(7,8-dihydroxy-2-(hydroxymethyl)-5-methylphenanthri...)
Affinity DataIC50: 2.00E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25542(7,8-dihydroxy-2-(2-hydroxyethyl)-5-methylphenanthr...)
Affinity DataIC50: 2.20E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25524(CHEMBL13045 | 17,18-dimethoxy-21-methyl-5,7-dioxa-...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25535(2-(hydroxymethyl)-7,8-dimethoxy-5-methylphenanthri...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25534(13,13-dimethyl-8-oxido-12,14-dioxa-8-azatetracyclo...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25533(8-oxido-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25532(7,8-dimethoxy-5-oxidophenanthridin-5-ium | chelery...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25531(8,13,13-trimethyl-12,14-dioxa-8-azatetracyclo[8.7....)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25529(7,8-dimethoxy-5-methylphenanthridin-5-ium iodide |...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25528(phenanthridine | 13,13-dimethyl-12,14-dioxa-8-azat...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25527(phenanthridine | 12,14-dioxa-8-azatetracyclo[8.7.0...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

LigandPNGBDBM25526(phenanthridine | 7,8-dimethoxyphenanthridine | che...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed