Compile Data Set for Download or QSAR
Report error Found 32 of Enz. Inhib. data with enzyme = 'Beta-2 adrenergic receptor' and Substrate = 'BDBM25747'
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25756(Betalok | Spesikor | {2-hydroxy-3-[4-(2-methoxyeth...)
Affinity DataKd:  129nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25771(salmeterol xinafoate | 4-(1-hydroxy-2-{[6-(4-pheny...)
Affinity DataKd:  1.47nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25770(Terbutaline,(+/-) | Brethine | 5-[2-(tert-butylami...)
Affinity DataKd:  2.40E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25769(Levalbuterol | Salbutamol,(+/-) | albuterol | Prov...)
Affinity DataKd:  759nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25768(ICI 118,551 | 1-[(7-methyl-2,3-dihydro-1H-inden-4-...)
Affinity DataKd:  0.550nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25767(tert-butyl(2-hydroxy-3-{[4-(morpholin-4-yl)-1,2,5-...)
Affinity DataKd:  0.210nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25766(Corgard | (2R,3S)-5-[3-(tert-butylamino)-2-hydroxy...)
Affinity DataKd:  2.5nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25765(tert-butyl[3-(2-chloro-5-methylphenoxy)-2-hydroxyp...)
Affinity DataKd:  0.140nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25764(ALPRENOLOL,(-) | CHEMBL266195 | ALPRENOLOL,(+) | A...)
Affinity DataKd:  0.910nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25763(5-[(2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl...)
Affinity DataKd:  7.94E+4nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25762(Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...)
Affinity DataKd:  141nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25761(Propanolol,(+/-) | PROPRANOLOL, l- | PROPRANOLOL,(...)
Affinity DataKd:  0.830nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25760(1-(naphthalen-2-yl)-2-(propan-2-ylamino)ethan-1-ol...)
Affinity DataKd:  44nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25759([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...)
Affinity DataKd:  0.400nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25758(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
Affinity DataKd:  9.30nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25747(4-[3-(tert-butylamino)-2-hydroxypropoxy]-2,3-dihyd...)
Affinity DataKd:  0.410nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKd:  832nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25754(2-[4-(2-{[(2R)-2-hydroxy-3-phenoxypropyl]amino}eth...)
Affinity DataKd:  1.38E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25753(Artrenolol | 2-{4-[2-hydroxy-3-(propan-2-ylamino)p...)
Affinity DataKd:  1.02E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25752([(2S)-3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2...)
Affinity DataKd:  42nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25751(Bisoprolol fumarate | Concor | [2-hydroxy-3-(4-{[2...)
Affinity DataKd:  200nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25750(N-(2-{[(2R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Affinity DataKd:  851nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25749(Practolol,(-) | Practolol,(+) | N-{4-[2-hydroxy-3-...)
Affinity DataKd:  1.02E+4nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25748(ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...)
Affinity DataKd:  85nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25746(cid_2685 | 2-hydroxy-5-{2-[(2-hydroxy-3-{4-[1-meth...)
Affinity DataKd:  776nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM27957((9S,10S)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataEC50:  6.90E+3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM27960(CHEMBL198059 | (2R,3S)-1-[(7-methyl-2,3-dihydro-1H...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/mole IC50: 3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM27959(El 737 | 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan...)
Affinity DataKi:  180nM ΔG°:  -9.10kcal/mole IC50: 330nM EC50:  9.10nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM27955((9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diaza...)
Affinity DataKi:  320nM ΔG°:  -8.77kcal/mole IC50: 620nM EC50:  8.70nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25769(Levalbuterol | Salbutamol,(+/-) | albuterol | Prov...)
Affinity DataKi:  510nM ΔG°:  -8.49kcal/mole IC50: 980nM EC50:  19nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM27958(Planipart | 1-(4-amino-3,5-dichlorophenyl)-2-(tert...)
Affinity DataKi:  570nM ΔG°:  -8.43kcal/mole IC50: 1.30E+3nM EC50:  6.20nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM27956(9-hydroxy-10-(propan-2-ylamino)-1,3-diazatricyclo[...)
Affinity DataKi:  580nM ΔG°:  -8.42kcal/mole IC50: 1.10E+3nM EC50:  13nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed