Compile Data Set for Download or QSAR
Report error Found 100 of Enz. Inhib. data with enzyme = 'Beta-secretase 2' and Substrate = 'Fluorescent Substrate'
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29777BDBM29777(BMCL193674 Compound 8 | 7,6,5 tricyclic sulfonamid...)
Affinity DataIC50: 28nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29777BDBM29777(BMCL193674 Compound 8 | 7,6,5 tricyclic sulfonamid...)
Affinity DataIC50: 28nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26503BDBM26503(3-ethyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trif...)
Affinity DataIC50: 59nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26503BDBM26503(3-ethyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trif...)
Affinity DataIC50: 59nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26503BDBM26503(3-ethyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-({[3-(trif...)
Affinity DataIC50: 59nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29796BDBM29796(sulfonamide tricyclic analogue, 7)
Affinity DataIC50: 75nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29792BDBM29792(7,6,5 tricyclic sulfonamide, 38)
Affinity DataIC50: 89nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29782BDBM29782(7,6,5 tricyclic sulfonamide, 22)
Affinity DataIC50: 96nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26506BDBM26506(N-[(2S,3R)-4-[(2,6-dimethylheptan-2-yl)amino]-3-hy...)
Affinity DataIC50: 110nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26506BDBM26506(N-[(2S,3R)-4-[(2,6-dimethylheptan-2-yl)amino]-3-hy...)
Affinity DataIC50: 114nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29789BDBM29789(7,6,5 tricyclic sulfonamide, 35)
Affinity DataIC50: 150nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26788BDBM26788(3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-2-...)
Affinity DataIC50: 177nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26508BDBM26508(BMCL193669 Compound 26 | N-[(2S,3R)-4-(cyclohexyla...)
Affinity DataIC50: 210nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26508BDBM26508(BMCL193669 Compound 26 | N-[(2S,3R)-4-(cyclohexyla...)
Affinity DataIC50: 210nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29805BDBM29805(sulfone tricyclic analogue, 18)
Affinity DataIC50: 260nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26510BDBM26510(N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...)
Affinity DataIC50: 263nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26510BDBM26510(N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...)
Affinity DataIC50: 263nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26510BDBM26510(N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...)
Affinity DataIC50: 263nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29793BDBM29793(7,6,5 tricyclic sulfonamide, 39)
Affinity DataIC50: 331nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29770BDBM29770(hydroxyethylamine derivative, 25)
Affinity DataIC50: 350nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29781BDBM29781(6,6,5 tricyclic sulfonamide, 21)
Affinity DataIC50: 350nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29804BDBM29804(sulfonamide tricyclic analogue, 15)
Affinity DataIC50: 370nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29783BDBM29783(6,6,5 tricyclic sulfonamide, 23)
Affinity DataIC50: 390nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 10145BDBM10145(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 420nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29799BDBM29799(sulfonamide tricyclic analogue, 10)
Affinity DataIC50: 430nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29806BDBM29806(sulfone tricyclic analogue, 19)
Affinity DataIC50: 450nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29775BDBM29775(BMCL193674 Compound 6 | 7,6,5 tricyclic sulfonamid...)
Affinity DataIC50: 490nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29775BDBM29775(BMCL193674 Compound 6 | 7,6,5 tricyclic sulfonamid...)
Affinity DataIC50: 490nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29794BDBM29794(sulfonamide tricyclic analogue, 5)
Affinity DataIC50: 590nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26777BDBM26777(3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-N-...)
Affinity DataIC50: 600nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29784BDBM29784(6,6,5 tricyclic sulfonamide, 25)
Affinity DataIC50: 620nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26782BDBM26782(N-[(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-{[(3...)
Affinity DataIC50: 630nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29791BDBM29791(7,6,5 tricyclic sulfonamide, 37)
Affinity DataIC50: 680nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26776BDBM26776(3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-ethoxy-N-[(2S,3...)
Affinity DataIC50: 760nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26786BDBM26786(3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-(ethylamino)-2-...)
Affinity DataIC50: 785nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29790BDBM29790(7,6,5 tricyclic sulfonamide, 36)
Affinity DataIC50: 940nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26773BDBM26773(3-(1,1-dioxo-1,2-thiazinan-2-yl)-5-ethoxy-N-[(2S,3...)
Affinity DataIC50: 1.02E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29788BDBM29788(7,6,5 tricyclic sulfonamide, 34)
Affinity DataIC50: 1.05E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26771BDBM26771(3-(2-cyanophenyl)-5-ethoxy-N-[(2S,3R)-3-hydroxy-1-...)
Affinity DataIC50: 1.05E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29803BDBM29803(sulfonamide tricyclic analogue, 14)
Affinity DataIC50: 1.14E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29808BDBM29808(sulfone tricyclic analogue, 21)
Affinity DataIC50: 1.15E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26502BDBM26502(BMCL193664 Compound 24 | BMCL181022 Compound 7 | B...)
Affinity DataIC50: 1.16E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29785BDBM29785(6,6,5 tricyclic sulfonamide, 27)
Affinity DataIC50: 1.17E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 29778BDBM29778(bicyclic sulfonamide analogue, 16)
Affinity DataIC50: 1.23E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26512BDBM26512(BMCL193669 Compound 28 | 3-ethyl-N-[(2S,3R)-3-hydr...)
Affinity DataIC50: 1.26E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26512BDBM26512(BMCL193669 Compound 28 | 3-ethyl-N-[(2S,3R)-3-hydr...)
Affinity DataIC50: 1.26E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26502BDBM26502(BMCL193664 Compound 24 | BMCL181022 Compound 7 | B...)
Affinity DataIC50: 1.41E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26502BDBM26502(BMCL193664 Compound 24 | BMCL181022 Compound 7 | B...)
Affinity DataIC50: 1.43E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26502BDBM26502(BMCL193664 Compound 24 | BMCL181022 Compound 7 | B...)
Affinity DataIC50: 1.43E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Gsk

LigandChemical structure of BindingDB Monomer ID 26774BDBM26774(3-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(2S,3R)-3-hydr...)
Affinity DataIC50: 1.45E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 100 total ) | Next | Last >>
Jump to: