Compile Data Set for Download or QSAR
Report error Found 16 of Enz. Inhib. data with enzyme = 'Botulinum neurotoxin type A2 [1-425]' and Substrate = 'SNAP-25-based peptide substrate'
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 23274BDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28913BDBM28913(N-[3-(4-nitrophenyl)-1H-pyrazol-5-yl]-2-sulfanylac...)
Affinity DataIC50: 2.90E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28906BDBM28906(N-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-2-sulfanyla...)
Affinity DataIC50: 4.80E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28917BDBM28917(N-[3-(3-chlorophenyl)-1H-pyrazol-5-yl]-2-sulfanyla...)
Affinity DataIC50: 5.60E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28911BDBM28911(N-[3-(4-bromophenyl)-1H-pyrazol-5-yl]-2-sulfanylac...)
Affinity DataIC50: 6.60E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28918BDBM28918(2-sulfanyl-N-{3-[2-(trifluoromethyl)phenyl]-1H-pyr...)
Affinity DataIC50: 7.20E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28912BDBM28912(2-sulfanyl-N-{3-[4-(trifluoromethyl)phenyl]-1H-pyr...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28919BDBM28919(2-sulfanyl-N-{3-[3-(trifluoromethyl)phenyl]-1H-pyr...)
Affinity DataIC50: 1.30E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28910BDBM28910(N-[3-(4-fluorophenyl)-1H-pyrazol-5-yl]-2-sulfanyla...)
Affinity DataIC50: 1.35E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28909BDBM28909(N-(3-phenyl-1H-pyrazol-5-yl)-2-sulfanylacetamide |...)
Affinity DataIC50: 1.45E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28914BDBM28914(N-[3-(4-methylphenyl)-1H-pyrazol-5-yl]-2-sulfanyla...)
Affinity DataIC50: 2.10E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28916BDBM28916(N-[3-(2-chlorophenyl)-1H-pyrazol-5-yl]-2-sulfanyla...)
Affinity DataIC50: 2.60E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28915BDBM28915(N-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-2-sulfanyl...)
Affinity DataIC50: 7.45E+4nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28905BDBM28905(N-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-3-sulfanylp...)
Affinity DataIC50: 1.95E+5nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28907BDBM28907(N-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-2-hydroxyac...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Absolute Science

LigandChemical structure of BindingDB Monomer ID 28908BDBM28908(N-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]acetamide | ...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed