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Report error Found 23 of Enz. Inhib. data with enzyme = 'Carbonic anhydrase 1' and Substrate = 'BDBM237235'
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239178(Thiazolidin-based CA inhibitor, 6b | (2S,5R)-5-met...)
Affinity DataKi:  4.43E+3nM ΔG°:  -7.30kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239173(Thiazolidin-based CA inhibitor, 3)
Affinity DataKi:  5.38E+3nM ΔG°:  -7.18kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239174(Thiazolidin-based CA inhibitor, 4)
Affinity DataKi:  5.51E+3nM ΔG°:  -7.17kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239177(Thiazolidin-based CA inhibitor, 6a | (2S,5S)-5-met...)
Affinity DataKi:  5.58E+3nM ΔG°:  -7.16kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239171(Thiazolidin-based CA inhibitor, 1)
Affinity DataKi:  6.80E+3nM ΔG°:  -7.04kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM237231(hCA inhibitor, 1)
Affinity DataKi:  1.37E+4nM ΔG°:  -6.63kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM237234(hCA inhibitor, 5)
Affinity DataKi:  2.43E+4nM ΔG°:  -6.29kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239175(Thiazolidin-based CA inhibitor, 5a)
Affinity DataKi:  2.75E+4nM ΔG°:  -6.22kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239176(Thiazolidin-based CA inhibitor, 5b)
Affinity DataKi:  2.94E+4nM ΔG°:  -6.18kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  3.62E+4nM ΔG°:  -6.05kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM60962(hCA inhibitor, 2)
Affinity DataKi:  3.72E+4nM ΔG°:  -6.04kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  4.00E+4nM ΔG°:  -6.00kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM10860(aromatic sulfonamide compound 6 | 4-(aminomethyl)b...)
Affinity DataKi:  4.19E+4nM ΔG°:  -5.97kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataKi:  4.29E+4nM ΔG°:  -5.95kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239172(Thiazolidin-based CA inhibitor, 2)
Affinity DataKi:  4.75E+4nM ΔG°:  -5.89kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM237232(hCA inhibitor, 3)
Affinity DataKi:  4.81E+4nM ΔG°:  -5.89kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM237233(hCA inhibitor, 4)
Affinity DataKi:  7.12E+4nM ΔG°:  -5.65kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM10859(CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...)
Affinity DataKi:  1.18E+5nM ΔG°:  -5.35kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239168(Carbonic anhydrase isoenzymes inhibitor, 14)
Affinity DataKi:  1.19E+6nM IC50: 3.22E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239170(Carbonic anhydrase isoenzymes inhibitor, 16)
Affinity DataKi:  2.59E+6nM IC50: 4.28E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239167(Carbonic anhydrase isoenzymes inhibitor, 13)
Affinity DataKi:  6.77E+6nM IC50: 6.92E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239166(Carbonic anhydrase isoenzymes inhibitor, 5)
Affinity DataKi:  3.25E+7nM IC50: 2.78E+4nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239169(Carbonic anhydrase isoenzymes inhibitor, 15)
Affinity DataKi:  8.36E+6nM IC50: 5.43E+4nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed