Compile Data Set for Download or QSAR
Report error Found 401 of Enz. Inhib. data with enzyme = 'Carbonic anhydrase 2' and Substrate = 'BDBM10856'
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11626(2-N-(4-amino-3-bromo-5-fluorobenzene)-1,3,4-thiadi...)
Affinity DataKi:  0.200nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11627(2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11628(5-(4-Amino-3,5-dichlorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  0.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11631(5-(4-Amino-3,5-dibromobenzenesulfonamido)-1,3,4-th...)
Affinity DataKi:  0.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  0.600nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11425(2-(3-hydroxyphenyl)-1,1-dioxo-3-[(prop-2-yn-1-ylam...)
Affinity DataIC50: 0.600nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11624(2-N-(4-amino-3-iodobenzene)-1,3,4-thiadiazole-2,5-...)
Affinity DataKi:  0.600nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11629(5-{[(4-amino-3-bromo-5-chlorophenyl)sulfonyl]amino...)
Affinity DataKi:  0.600nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11632(5-{[(4-amino-3-bromo-5-iodophenyl)sulfonyl]amino}-...)
Affinity DataKi:  0.600nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11623(5-(4-Amino-3-bromobenzenesulfonamido)-1,3,4-thiadi...)
Affinity DataKi:  0.700nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM33280(CHEMBL153094 | aliphatic sulfamate, 2)
Affinity DataKi:  0.700nM ΔG°:  -12.4kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11413(Compound 17g1 | 2-cyclohexyl-3-(morpholin-4-ylmeth...)
Affinity DataIC50: 0.790nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11621(2-N-(4-amino-3-fluorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  0.800nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11630(2-N-(4-amino-3-chloro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  0.800nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11394(Compound 5b | 2-[2-(4-Morpholinyl)ethyl]-2H-thieno...)
Affinity DataIC50: 0.820nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11633(5-(4-Amino-3,5-diiodobenzenesulfonamido)-1,3,4-thi...)
Affinity DataKi:  0.900nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  0.900nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11393(2-{2-[bis(2-methoxyethyl)amino]ethyl}-1,1-dioxo-2H...)
Affinity DataIC50: 0.910nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11405(Compound 17b4 | 2-Ethyl-3-[[bis(2-hydroxyethyl)ami...)
Affinity DataIC50: 0.960nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11395(Compound 5c | 2-[2-[4-Acetyl-(1-piperazinyl)]ethyl...)
Affinity DataIC50: 0.960nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11411(3-(morpholin-4-ylmethyl)-1,1-dioxo-2-(prop-2-en-1-...)
Affinity DataIC50: 0.990nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11029(CHEMBL184674 | 2-acetamido-5-sulfonamidoindane | N...)
Affinity DataKi:  1nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11401(2-Ethyl-3-[[bis(2-methoxyethyl)amino]methyl]-2H-th...)
Affinity DataIC50: 1.04nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11422(Compound 17m1 | 2-(3,4-Dimethoxyphenyl)-3-[(4-morp...)
Affinity DataIC50: 1.05nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11400(2-Ethyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]...)
Affinity DataIC50: 1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11399(Compound 17a7 | 3-{[(2-methoxyethyl)(prop-2-en-1-y...)
Affinity DataIC50: 1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11390(2-(3-hydroxyphenyl)-3-(morpholin-4-ylmethyl)-1,1-d...)
Affinity DataIC50: 1.15nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11421(3-{[(2-hydroxyethyl)amino]methyl}-2-(3-methoxyphen...)
Affinity DataIC50: 1.16nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11398(3-[N-(2-Methoxyethyl)-N-methylamino]methyl]-2-meth...)
Affinity DataIC50: 1.17nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11616(aminobenzolamide deriv. 40 | 5-(4-Acetamido-3-fluo...)
Affinity DataKi:  1.20nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11030(2-propyl-N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)...)
Affinity DataKi:  1.20nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11406(Compound 17c1 | 3-[(4-Morpholinyl)methyl]-2-propyl...)
Affinity DataIC50: 1.24nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11391(2-(3-Methoxyphenyl)-3-[(4-morpholinyl)methyl]-2H-t...)
Affinity DataIC50: 1.27nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11392((4R)-4-amino-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4...)
Affinity DataIC50: 1.28nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11617(5-(4-Acetamido-3-chlorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  1.30nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11636(N-[2-(diethylamino)ethyl]-4-[(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  1.40nM ΔG°:  -11.9kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11412(2-(cyclopropylmethyl)-3-(morpholin-4-ylmethyl)-1,1...)
Affinity DataIC50: 1.41nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11409(Compound 17d1 | 2-(1-Methylethyl)-3-[(4-morpholiny...)
Affinity DataIC50: 1.46nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11407(3-{[bis(2-methoxyethyl)amino]methyl}-1,1-dioxo-2-p...)
Affinity DataIC50: 1.48nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11423(Compound 17n1 | 2-[4-(morpholin-4-yl)phenyl]-3-(mo...)
Affinity DataIC50: 1.5nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11634(heterocyclic sulfonamide compound 38 | 2,3,4,5,6-p...)
Affinity DataKi:  1.5nM ΔG°:  -11.9kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11618(5-(4-Acetamido-3-bromobenzenesulfonamido)-1,3,4-th...)
Affinity DataKi:  1.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11408(1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-propyl...)
Affinity DataIC50: 1.52nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11410(Compound 17d8 | 1,1-dioxo-3-[(prop-2-yn-1-ylamino)...)
Affinity DataIC50: 1.60nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11424(Compound 17o1 | 2-(3-Hydroxypropyl)-3-(4-morpholin...)
Affinity DataIC50: 1.62nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11397(2-methyl-3-(morpholin-4-ylmethyl)-1,1-dioxo-2H-1,7...)
Affinity DataIC50: 1.66nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11619(5-(4-Acetamido-3-iodobenzenesulfonamido)-1,3,4-thi...)
Affinity DataKi:  1.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM10870(aminobenzolamide deriv. 43 | CHEMBL268439 | 2-N-(4...)
Affinity DataKi:  2nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM10870(aminobenzolamide deriv. 43 | CHEMBL268439 | 2-N-(4...)
Affinity DataKi:  2nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
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