Compile Data Set for Download or QSAR
Report error Found 174 of Enz. Inhib. data with enzyme = 'Carboxylic ester hydrolase' and Substrate = 'BDBM8978'
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9007(7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic...)
Affinity DataIC50: 0.950nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9013(6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic ...)
Affinity DataIC50: 2nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9014(N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-te...)
Affinity DataIC50: 2.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9018(N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-6-(1,2,3,4-te...)
Affinity DataIC50: 3.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9008(6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]...)
Affinity DataIC50: 5.20nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 8.10nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9011(6-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 8.20nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 10nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9006(N-[2-(1H-indol-3-yl)ethyl]-6-(1,2,3,4-tetrahydroac...)
Affinity DataIC50: 12nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8980(N-[(1-benzylpiperidin-4-yl)methyl]-2-(1,2,3,4-tetr...)
Affinity DataIC50: 12.4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10742(1-amino-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarb...)
Affinity DataIC50: 14nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9010(6-[(8-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]...)
Affinity DataIC50: 15nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 19nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9016(6-(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 22nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 44nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10743(1-amino-2,3-dihydro-1H-inden-4-yl N-ethyl-N-methyl...)
Affinity DataIC50: 54nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9015(6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50: 55nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8979(CHEMBL486901 | N-[2-(1-benzylpiperidin-4-yl)ethyl]...)
Affinity DataIC50: 76nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9012(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 85nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 92nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 92nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9017(7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)am...)
Affinity DataIC50: 100nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataIC50: 100nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10478(A2A.2HCl | CHEMBL213377 | N-[2-(1,2,3,4-tetrahydro...)
Affinity DataIC50: 102nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8964(CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...)
Affinity DataIC50: 105nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9440(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]q...)
Affinity DataIC50: 110nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9047(CHEMBL73800 | N-[6-(1,2,3,4-tetrahydroacridin-9-yl...)
Affinity DataIC50: 119nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9441(N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]qu...)
Affinity DataIC50: 126nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9430(dimethyl[7-(1,2,3,4-tetrahydroacridin-9-ylamino)he...)
Affinity DataIC50: 143nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 149nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10479(N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]-...)
Affinity DataIC50: 152nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10469(CHEMBL424707 | Bis-THA inhibitor 8 | N-[9-(1,2,3,4...)
Affinity DataIC50: 155nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9442(CHEMBL1082739 | N-[9-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 156nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9436(N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]py...)
Affinity DataIC50: 157nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 167nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9431(dimethyl[8-(1,2,3,4-tetrahydroacridin-9-ylamino)oc...)
Affinity DataIC50: 170nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10469(CHEMBL424707 | Bis-THA inhibitor 8 | N-[9-(1,2,3,4...)
Affinity DataIC50: 190nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9437(N-[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]py...)
Affinity DataIC50: 200nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9426(N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...)
Affinity DataIC50: 202nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50: 210nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9432(N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,9...)
Affinity DataIC50: 237nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50: 240nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10833(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 240nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10480(A4A.2HCl | N-[4-(1,2,3,4-tetrahydroacridin-9-ylami...)
Affinity DataIC50: 252nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10793(7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 290nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM9435(N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,7-...)
Affinity DataIC50: 302nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM10778(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 310nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM8962(CHEMBL179732 | N-[5-(1,2,3,4-tetrahydroacridin-9-y...)
Affinity DataIC50: 329nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10442(N-heptyl-1,2,3,4-tetrahydroacridin-9-amine hydroch...)
Affinity DataIC50: 340nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
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