Compile Data Set for Download or QSAR
Report error Found 9 of Enz. Inhib. data with enzyme = 'Caspase-2' and Substrate = 'Caspase-2 Fluorogenic Substrate Ac-Val-Asp-Val-Ala-Asp-AFC'
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 221BDBM221(Pyridine Scaffold 4 | 5-{[(5-{[(2S)-1-carboxy-3-ox...)
Affinity DataKi:  960nM ΔG°:  -8.20kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 220BDBM220(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
Affinity DataKi:  9.00E+3nM ΔG°:  -6.88kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 222BDBM222((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Affinity DataKi:  1.10E+4nM ΔG°:  -6.76kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 224BDBM224((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Affinity DataKi:  1.60E+4nM ΔG°:  -6.54kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 225BDBM225(Thiophene Scaffold 66a | (S)-5-5-(1-Carboxymethyl-...)
Affinity DataKi:  2.10E+4nM ΔG°:  -6.38kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 219BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Affinity DataKi:  3.00E+4nM ΔG°:  -6.17kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 223BDBM223(5-{[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methyl...)
Affinity DataKi:  3.00E+4nM ΔG°:  -6.17kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 227BDBM227(Heterocyclic deriv. 69b | (S)-5-({5-[1-Carboxymeth...)
Affinity DataKi:  3.70E+4nM ΔG°:  -6.04kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-2(Human)
Sunesis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 226BDBM226(Thiophene Scaffold 66b | (S)-5-({5-[1-Carboxymethy...)
Affinity DataKi:  6.40E+4nM ΔG°:  -5.72kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed