Compile Data Set for Download or QSAR
Report error Found 14 of Enz. Inhib. data with enzyme = 'Caspase-3' and Substrate = 'Caspase-3 (7) Fluorogenic Substrate'
TargetCaspase-3(Mouse)
Stanford University

LigandChemical structure of BindingDB Monomer ID 228619BDBM228619(US9345789, Z-DEVD-FMK)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetCaspase-3(Mouse)
Stanford University

LigandChemical structure of BindingDB Monomer ID 36333BDBM36333(LI-0 | Legumain Inhibitor -0)
Affinity DataIC50: 2.80E+3nMpH: 7.4 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10215BDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  4.30E+3nM ΔG°:  -7.24kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10218BDBM10218(phenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-th...)
Affinity DataIC50: 4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10216BDBM10216(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thi...)
Affinity DataIC50: 4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10219BDBM10219(BI-9B11 | [2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,...)
Affinity DataIC50: 5.50E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10222BDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50: 7.40E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10223BDBM10223(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methy...)
Affinity DataIC50: 8.20E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10225BDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50: 1.28E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10221BDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50: 1.29E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10217BDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50: 1.33E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10224BDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50: 1.50E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 10220BDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2006
Entry Details Article
PubMed
TargetCaspase-3(Mouse)
Stanford University

LigandChemical structure of BindingDB Monomer ID 36332BDBM36332(LI-1 | Legumain Inhibitor -1)
Affinity DataIC50: 8.90E+5nMpH: 7.4 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2011
Entry Details Article
PubMed