Compile Data Set for Download or QSAR
Report error Found 85 of Enz. Inhib. data with enzyme = 'Caspase-7' and Substrate = 'Caspase Fluorogenic Substrate'
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10675((3S)-3-[(2S)-2-[(2S)-2-[(3S)-3-formamido-3-(phenyl...)
Affinity DataIC50: 8.40nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 8.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10350(1-Benzyl-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine...)
Affinity DataIC50: 14.1nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10335((S)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxyme...)
Affinity DataIC50: 14.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10353(1-[(4-fluorophenyl)methyl]-5-{[(2S)-2-[(pyridin-3-...)
Affinity DataIC50: 15.1nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10351(1-[(4-methoxyphenyl)methyl]-5-{[(2S)-2-[(pyridin-3...)
Affinity DataIC50: 15.1nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10345((S)-1-(6-Fluoropyridin-3-ylmethyl)-5-(2-phenoxymet...)
Affinity DataIC50: 17nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10343((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-azetidin...)
Affinity DataIC50: 21nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10330((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-pyrroli...)
Affinity DataIC50: 21.8nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10337(1-[(6-fluoropyridin-2-yl)methyl]-5-{[(2S)-2-(pheno...)
Affinity DataIC50: 22.2nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10347((S)-1-(6-Fluoropyridin-2-yl-methyl)-5-(2-phenoxyme...)
Affinity DataIC50: 22.7nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10331((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...)
Affinity DataIC50: 23nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10341((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)
Affinity DataIC50: 23.2nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 23.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10653(Compound 3 | (3S)-5-{[(2-chloro-6-fluorophenyl)met...)
Affinity DataIC50: 24nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10344((S)-1-(2-Fluorobenzyl)-5-(2-phenoxymethyl-azetidin...)
Affinity DataIC50: 26nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10342(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-(p...)
Affinity DataIC50: 26.7nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10323(JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...)
Affinity DataIC50: 28nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10340(1-benzyl-5-{[(2S)-2-(phenoxymethyl)azetidine-1-]su...)
Affinity DataIC50: 29.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10333(Acetic Acid (S)-4-[2,3-Dioxo-5-(2-phenoxymethyl-py...)
Affinity DataIC50: 34.8nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10332(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-(p...)
Affinity DataIC50: 41nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10334((S)-1-(4-Hydroxybenzyl)-5-(2-phenoxymethyl-pyrroli...)
Affinity DataIC50: 44nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50: 58nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10555((3S)-5-(benzylsulfanyl)-3-[(2S)-2-{2-hydroxy-2-[2-...)
Affinity DataIC50: 63nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 87nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10551((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[2-(5-bromo-2-me...)
Affinity DataIC50: 91nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10349(1-methyl-5-{[(2S)-2-[(pyridin-3-yloxy)methyl]pyrro...)
Affinity DataIC50: 94.9nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10554((3S)-5-(benzylsulfanyl)-3-[(2S)-2-{1-[2-methoxy-5-...)
Affinity DataIC50: 97nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10674((3S)-5-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}...)
Affinity DataIC50: 120nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10552((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[1-(5-acetyl-2-m...)
Affinity DataIC50: 130nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10346((S)-1-(2-Fluoropyridin-4-yl-methyl)-5-(2-phenoxyme...)
Affinity DataIC50: 135nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10556((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[2-hydroxy-2-(5-...)
Affinity DataIC50: 135nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10535((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[(2R)-2-(5-bromo...)
Affinity DataIC50: 139nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10354(5-(2-(Pyridin-4-yl-oxymethyl)-pyrrolidine-1-sulfon...)
Affinity DataIC50: 142nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10348(5-{[(2S)-2-[(pyridin-3-yloxy)methyl]pyrrolidine-1-...)
Affinity DataIC50: 215nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10527(valine aspartyl ketone 29 | BROMOMETHOXYPHENYL INH...)
Affinity DataIC50: 284nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10527(valine aspartyl ketone 29 | BROMOMETHOXYPHENYL INH...)
Affinity DataIC50: 285nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10553((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[2-(5-acetyl-2-m...)
Affinity DataIC50: 290nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)
Affinity DataIC50: 310nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10671((3S)-3-[(2S)-2-{1-[5-(carboxymethoxy)-2-ethoxyphen...)
Affinity DataIC50: 360nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10339(1-methyl-5-{[(2S)-2-(phenoxymethyl)azetidine-1-]su...)
Affinity DataIC50: 363nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10318(5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}...)
Affinity DataIC50: 540nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10549((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[2-(2,5-dimethox...)
Affinity DataIC50: 545nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10552((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[1-(5-acetyl-2-m...)
Affinity DataIC50: 555nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10537((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[(2R)-2-hydroxy-...)
Affinity DataIC50: 1.05E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10338(5-{[(2S)-2-(phenoxymethyl)azetidine-1-]sulfonyl}-2...)
Affinity DataIC50: 1.35E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10661((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[(5-fluoro-1H-in...)
Affinity DataIC50: 1.40E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10660((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[(3,5-dibromophe...)
Affinity DataIC50: 1.50E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10669((3S)-5-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}...)
Affinity DataIC50: 1.70E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Merck Frosst Canada

LigandPNGBDBM10662((3S)-3-[(2S)-2-[1-(2,5-dimethoxyphenyl)acetamido]-...)
Affinity DataIC50: 1.80E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2006
Entry Details Article
PubMed
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