Compile Data Set for Download or QSAR
Report error Found 20 of Enz. Inhib. data with enzyme = 'Caspase-8' and Substrate = 'Caspase-8 Substrate'
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM10357((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 4.20nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29579(isatin Michael acceptor (IMA) analogue, 13b)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29587(isatin Michael acceptor (IMA) analogue, 19c)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29586(isatin Michael acceptor (IMA) analogue, 19b)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29585(isatin Michael acceptor (IMA) analogue, 19a)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29584(isatin Michael acceptor (IMA) analogue, 18c)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29583(isatin Michael acceptor (IMA) analogue, 18b)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29582(isatin Michael acceptor (IMA) analogue, 18a)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29580(isatin Michael acceptor (IMA) analogue, 13c)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29569(isatin sulfonamide, 6 | acs.jmedchem.1c00409_ST.54...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29578(isatin Michael acceptor (IMA) analogue, 13a)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29577(isatin Michael acceptor (IMA) analogue, 12c)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29576(isatin Michael acceptor (IMA) analogue, 12b)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29575(isatin Michael acceptor (IMA) analogue, 12a)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29574(isatin Michael acceptor (IMA) analogue, 11c)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29573(isatin Michael acceptor (IMA) analogue, 11b)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29572(isatin Michael acceptor (IMA) analogue, 11a)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29570(isatin sulfonamide, 9c)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed