Compile Data Set for Download or QSAR
Report error Found 29 of Enz. Inhib. data with enzyme = 'Cathepsin B' and Substrate = 'BDBM16498'
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16511((2S)-1-[(2S)-2-{[(2S,3S)-3-{[(1S)-1-({[(2-methoxy-...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16499(CA inhibitor 2 | EtO-tES-Ile-Ala-OH | CA075 | (2S)...)
Affinity DataIC50: 23nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16500(CA inhibitor 3 | EtO-tES-Ile-Ile-OH | (2S)-2-[(2S,...)
Affinity DataIC50: 24nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16502(BzlNH-tES-Ile-Pro-OH | CA inhibitor 5 | N-{[(2S,3S...)
Affinity DataIC50: 29nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16509(CA074 | CHEMBL490920 | (2S)-1-[(2S,3S)-3-methyl-2-...)
Affinity DataIC50: 38nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16510(HO-tES-Leu-NH-CH2-CH2CH(CH3)2 | (2S,3S)-3-[[(2S)-4...)
Affinity DataIC50: 40nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16508((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50: 120nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16501(EtO-tES-Thr-Ile-OH | (2S)-2-[(2S,3R)-2-{[(2S,3S)-3...)
Affinity DataIC50: 410nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16504(benzyl (2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(pro...)
Affinity DataIC50: 9.10E+3nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16506(CA inhibitor 9 | (2S)-1-(2-{[(2S,3S)-3-(ethoxycarb...)
Affinity DataIC50: 1.53E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16497((2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...)
Affinity DataIC50: 2.40E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16505(BzlNH-tES-Ile-Pro-OBzl | benzyl N-{[(2S,3S)-3-(ben...)
Affinity DataIC50: 4.60E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16503(CA074Me | CA inhibitor 6 | methyl N-{[(2S,3S)-3-(p...)
Affinity DataIC50: 6.80E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86095(2-Cyanopyrrolidine Derivative, 24)
Affinity DataKi:  5.30E+3nM ΔG°:  -7.14kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86096(2-Cyanopyrrolidine Derivative, 25)
Affinity DataKi:  8.60E+3nM ΔG°:  -6.86kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86094(2-Cyanopyrrolidine Derivative, 23)
Affinity DataKi:  6.70E+4nM ΔG°:  -5.65kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86099(2-Cyanopyrrolidine Derivative, 28)
Affinity DataKi:  7.50E+4nM ΔG°:  -5.59kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86093(2-Cyanopyrrolidine Derivative, 22)
Affinity DataKi:  8.50E+4nM ΔG°:  -5.51kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86094(2-Cyanopyrrolidine Derivative, 23)
Affinity DataKi:  9.20E+4nM ΔG°:  -5.47kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86097(2-Cyanopyrrolidine Derivative, 26)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86098(2-Cyanopyrrolidine Derivative, 27)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86100(2-Cyanopyrrolidine Derivative, 29)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86093(2-Cyanopyrrolidine Derivative, 22)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86095(2-Cyanopyrrolidine Derivative, 24)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86096(2-Cyanopyrrolidine Derivative, 25)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86097(2-Cyanopyrrolidine Derivative, 26)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86098(2-Cyanopyrrolidine Derivative, 27)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86099(2-Cyanopyrrolidine Derivative, 28)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
The M. S. University of Baroda

LigandPNGBDBM86100(2-Cyanopyrrolidine Derivative, 29)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed