Compile Data Set for Download or QSAR
Report error Found 57 of Enz. Inhib. data with enzyme = 'Cathepsin D' and Substrate = 'Cathepsin D Peptide Substrate'
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29747(macrocyclic peptidomimetic, 3a)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29752(macrocyclic peptidomimetic, 3f)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29751(macrocyclic peptidomimetic, 3e)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29749(macrocyclic peptidomimetic, 3c)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29748(NVP-ARV99 | macrocyclic peptidomimetic, 3b)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29746(N-methyl-alanine tripeptide inhibitor, 2b)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29753(macrocyclic peptidomimetic, 3g)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29745(hydroxyethylene tripeptide inhibitor, 2a)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataIC50: 6nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16055((2S)-N-[(1S)-1-{[(1S,2S)-1-[(1R,2R)-2-{[(1S)-1-(bu...)
Affinity DataIC50: 10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16088(AXF | (2R,4S)-4-[(4aS,12R,15S,17aS)-15-methyl-14,1...)
Affinity DataIC50: 10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16049((4S)-4-[(2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S...)
Affinity DataIC50: 10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16054((2S)-N-[(1S)-1-{[(1S,2S)-1-[(1R,2R)-2-{[(1S)-1-(bu...)
Affinity DataIC50: 10nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16084(tert-butyl N-[(3R,6S,9R,13E)-3-[(1S,3R)-3-{[(1S)-1...)
Affinity DataIC50: 11nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16065(tert-butyl N-[(3R,6S,9R)-3-[(1S,3R)-3-(butylcarbam...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16053(N-acetyl-L-leucyl-N-{(1S)-1-[(S)-[(1R,2R)-2-{[(1S)...)
Affinity DataIC50: 25nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16066(tert-butyl {(3R,6S,9R)-3-[(1S,3R)-4-(butylamino)-1...)
Affinity DataIC50: 25nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16083(tert-butyl {(3R,6S,9R,13Z)-3-[(1S,3R)-4-{[(1S)-1-(...)
Affinity DataIC50: 50nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16057(N-acetyl-L-leucyl-N-{(1S)-1-[(S)-[(1R,2R)-2-{[(1S)...)
Affinity DataIC50: 56nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16056((1R,2R)-N-butyl-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-aceta...)
Affinity DataIC50: 60nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16050((2S)-2-[(2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S...)
Affinity DataIC50: 60nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16060((2S)-N-[(1S)-1-{[(1S,2S)-1-[(2R,3R)-2-{[(1S)-1-(bu...)
Affinity DataIC50: 70nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16052((2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-acet...)
Affinity DataIC50: 90nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16048((4S)-4-amino-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1R...)
Affinity DataIC50: 98nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16081(tert-butyl N-[(3S,6S,9R,13Z)-3-[(1S,3R)-3-(butylca...)
Affinity DataIC50: 110nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16059((2S)-N-[(1S)-1-{[(1S,2S)-1-[(3S,4R)-4-{[(1S)-1-(bu...)
Affinity DataIC50: 130nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16076((2R,4S)-4-[(3R,6S,9R,13E)-9-amino-6-methyl-5,8-dio...)
Affinity DataIC50: 150nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16064(tert-butyl N-[(3R,6S,9R)-3-[(1S,3R)-3-(butylcarbam...)
Affinity DataIC50: 180nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16069(tert-butyl N-[(3R,6S,9R,13E)-3-[(1S,3R)-3-(butylca...)
Affinity DataIC50: 190nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16078((2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-N,4...)
Affinity DataIC50: 190nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16067(tert-butyl [(5R,8S,11R)-5-[(1S,3R)-4-(butylamino)-...)
Affinity DataIC50: 195nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16087((2R,4S)-N-butyl-4-hydroxy-2-methyl-4-[(4aR,7E,12R,...)
Affinity DataIC50: 200nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16077((2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-4-m...)
Affinity DataIC50: 260nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16061((2S)-N-[(1S)-1-{[(1S,2S)-1-[(2R,3S)-2-{[(1S)-1-(bu...)
Affinity DataIC50: 280nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29744(hydroxyethylene tripeptide inhibitor, 1)
Affinity DataIC50: 370nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16063(N-acetyl-L-leucyl-N-{(1S)-1-[(S)-[(1R,2R)-2-{[(1S)...)
Affinity DataIC50: 430nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16068(tert-butyl {(3R,6S,9R,13Z)-3-[(1S,3R)-4-(butylamin...)
Affinity DataIC50: 460nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16080(Olefins were mixtures of cis and trans isomers. | ...)
Affinity DataIC50: 910nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16079(tert-butyl {(3S,6S,9S)-3-[(1S,3R)-4-(butylamino)-1...)
Affinity DataIC50: 1.11E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16058((2S)-N-[(1S)-1-{[(1S,2S)-1-[(3S,4S)-4-{[(1S)-1-(bu...)
Affinity DataIC50: 1.23E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16072((2R,4S)-N-butyl-4-[(3R,6S,9R)-9-acetamido-6-methyl...)
Affinity DataIC50: 1.25E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16062(N-acetyl-L-leucyl-N-{(1S)-1-[(S)-[(1R,2R)-2-{[(1S)...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29750(macrocyclic peptidomimetic, 3d)
Affinity DataIC50: 1.70E+3nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16071((2R,4S)-4-[(3R,6S,9R)-9-(acetylamino)-6-methyl-5,8...)
Affinity DataIC50: 1.70E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16073((2R,4S)-4-[(5R,8S,11R)-11-(acetylamino)-8-methyl-7...)
Affinity DataIC50: 3.60E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16075((2R,4S)-N-butyl-4-hydroxy-2-methyl-4-[(3R,6S,13E)-...)
Affinity DataIC50: 3.90E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16082(Olefins were mixtures of cis and trans isomers. | ...)
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16051(truncated OM99-2 cyclopentano analog 5 | L-alpha-g...)
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM16092((2R,4S)-4-[(4aS,12R,15S,17aR)-15-methyl-14,17-diox...)
Affinity DataIC50: 6.90E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29754(macrocyclic peptidomimetic, 3h)
Affinity DataIC50: 8.10E+3nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
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