Compile Data Set for Download or QSAR
Report error Found 24 of Enz. Inhib. data with enzyme = 'Cathepsin L2' and Substrate = 'BDBM22047'
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31992(Dipeptidyl nitrile inhibitor, 25)
Affinity DataIC50: 200nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31977(Dipeptidyl nitrile inhibitor, 10)
Affinity DataIC50: 200nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31980(Dipeptidyl nitrile inhibitor, 13)
Affinity DataIC50: 200nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31988(Dipeptidyl nitrile inhibitor, 21)
Affinity DataIC50: 251nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31972(Dipeptidyl nitrile inhibitor, 5)
Affinity DataIC50: 398nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50: 398nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31989(Dipeptidyl nitrile inhibitor, 22)
Affinity DataIC50: 501nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31990(Dipeptidyl nitrile inhibitor, 23)
Affinity DataIC50: 501nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31991(Dipeptidyl nitrile inhibitor, 24)
Affinity DataIC50: 501nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31970(Dipeptidyl nitrile inhibitor, 1)
Affinity DataIC50: 794nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31975(Dipeptidyl nitrile inhibitor, 8)
Affinity DataIC50: 794nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31974(Dipeptidyl nitrile inhibitor, 7)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31984(Dipeptidyl nitrile inhibitor, 17)
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31985(Dipeptidyl nitrile inhibitor, 18)
Affinity DataIC50: 1.26E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31986(Dipeptidyl nitrile inhibitor, 19)
Affinity DataIC50: 1.26E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31978(Dipeptidyl nitrile inhibitor, 11)
Affinity DataIC50: 1.59E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31987(Dipeptidyl nitrile inhibitor, 20)
Affinity DataIC50: 2.51E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31983(Dipeptidyl nitrile inhibitor, 16)
Affinity DataIC50: 3.16E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31979(Dipeptidyl nitrile inhibitor, 12)
Affinity DataIC50: 3.98E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31981(Dipeptidyl nitrile inhibitor, 14)
Affinity DataIC50: 3.98E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31976(Dipeptidyl nitrile inhibitor, 9)
Affinity DataIC50: 5.01E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31971(Dipeptidyl nitrile inhibitor, 4)
Affinity DataIC50: 6.31E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31973(Dipeptidyl nitrile inhibitor, 6)
Affinity DataIC50: 6.31E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

LigandPNGBDBM31982(Dipeptidyl nitrile inhibitor, 15)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details Article
PubMed