Compile Data Set for Download or QSAR
Report error Found 8 of Enz. Inhib. data with enzyme = 'Cathepsin S' and Substrate = 'BDBM19480'
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19488(2-{2-[2,3-difluoro-4-(2-methylpropyl)phenyl]phenox...)
Affinity DataKi:  9.60nM ΔG°:  -11.4kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19484(N-[(1S)-1-{1-[(1S)-1-cyanopentyl]-1H-1,2,3-triazol...)
Affinity DataKi:  15nM ΔG°:  -11.1kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19483(N-[(1S)-1-{1-[(1S)-1-cyanopentyl]-1H-1,2,3-triazol...)
Affinity DataKi:  18nM ΔG°:  -11.0kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  48.7nM ΔG°:  -10.4kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19482(N-[(1S)-1-{1-[(1S)-1-cyanopentyl]-1H-1,2,3-triazol...)
Affinity DataKi:  200nM ΔG°:  -9.50kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19481(N-[(2S)-2-{1-[(1S)-1-cyanopentyl]-1H-1,2,3-triazol...)
Affinity DataKi:  420nM ΔG°:  -9.04kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  490nM ΔG°:  -8.95kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19479(N-[(2S)-2-{1-[(1S)-1-cyanopentyl]-1H-1,2,3-triazol...)
Affinity DataKi:  1.20E+3nM ΔG°:  -8.40kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed