Compile Data Set for Download or QSAR
Report error Found 21 of Enz. Inhib. data with enzyme = 'cAMP-dependent protein kinase catalytic subunit alpha' and Substrate = 'PKA-specific peptide substrate'
LigandPNGBDBM16231([2-(4-chlorophenyl)-2-[4-(9H-purin-6-yl)phenyl]eth...)
Affinity DataIC50: 15nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM15131(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 27nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM16232(6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-...)
Affinity DataIC50: 33nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM15211(CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...)
Affinity DataIC50: 73nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM15211(CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...)
Affinity DataIC50: 73nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM16222(N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}amino)ethyl]is...)
Affinity DataIC50: 170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM16222(N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}amino)ethyl]is...)
Affinity DataIC50: 170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM15218(N-{[(2S,4S)-4-[(4-chlorophenyl)methoxy]pyrrolidin-...)
Affinity DataIC50: 170nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM16222(N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}amino)ethyl]is...)
Affinity DataIC50: 170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM15220(N-[(3S,5S)-5-{[(4-chlorophenyl)methoxy]methyl}pyrr...)
Affinity DataIC50: 320nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15216(Isoquinoline-5-sulfonic acid (2S,4R)-(4-(4-chlorob...)
Affinity DataIC50: 400nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15196(Isoquinoline-5-sulfonic acid (2-(2-(3-chlorobenzyl...)
Affinity DataIC50: 410nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15215(N-[(3S,5S)-5-{[(4-chlorophenyl)methoxy]methyl}pyrr...)
Affinity DataIC50: 420nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM16229(2-phenyl-1-[4-(9H-purin-6-yl)phenyl]ethan-1-amine ...)
Affinity DataIC50: 610nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM15195(N-[2-({2-[(2-chlorophenyl)methoxy]ethyl}amino)ethy...)
Affinity DataIC50: 1.00E+3nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15221(N-[(3S,5S)-5-{[(4-chlorophenyl)methoxy]methyl}pyrr...)
Affinity DataIC50: 1.30E+3nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15204(N-(piperidin-4-yl)isoquinoline-5-sulfonamide | Iso...)
Affinity DataIC50: 3.90E+3nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM16224(N-methyl-1-[4-(9H-purin-6-yl)phenyl]methanamine | ...)
Affinity DataIC50: 5.20E+3nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM15210(N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide...)
Affinity DataIC50: 5.30E+3nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM16225(N-methyl-1-[3-(9H-purin-6-yl)phenyl]methanamine | ...)
Affinity DataIC50: 5.50E+3nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM15207(Isoquinoline-5-sulfonic acid trans-(4-aminocyclohe...)
Affinity DataIC50: 5.70E+3nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed