Compile Data Set for Download or QSAR
Report error Found 30 of Enz. Inhib. data with enzyme = 'cAMP-dependent protein kinase catalytic subunit alpha' and Substrate = 'biotinylated kemptide'
LigandChemical structure of BindingDB Monomer ID 16958BDBM16958(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-eth...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
8/1/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15067BDBM15067(13a (S-) | 6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)pro...)
Affinity DataIC50: 2.10nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16564BDBM16564((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50: 5nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16954BDBM16954(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-chl...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15131BDBM15131(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16784BDBM16784(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 6.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
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Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16588BDBM16588((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-pyr...)
Affinity DataIC50: 7nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16978BDBM16978(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 8nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
8/1/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16537BDBM16537(5-{5-[(2S)-2-amino-3-(2,3-difluorophenyl)propoxy]p...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16587BDBM16587(3-[(2S)-2-amino-3-[3-(trifluoromethyl)phenyl]propo...)
Affinity DataIC50: 13nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16586BDBM16586((2S)-1-{[5-(3-chloro-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50: 15nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16532BDBM16532(pyrazolopyridine analog, 9g | (2S)-1-(1H-indol-3-y...)
Affinity DataIC50: 15nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16547BDBM16547(5-{5-[(2S)-2-amino-3-(4-bromophenyl)propoxy]pyridi...)
Affinity DataIC50: 15nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16785BDBM16785(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 16nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
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Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKi:  16nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16783BDBM16783(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 18nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16791BDBM16791(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...)
Affinity DataIC50: 32nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16794BDBM16794(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-ethenyl-1H-p...)
Affinity DataIC50: 32nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15022BDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50: 38nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15022BDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50: 38nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16792BDBM16792(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-chloro-1H-py...)
Affinity DataIC50: 46nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16968BDBM16968(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 48nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16788BDBM16788(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 58nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16585BDBM16585((2S)-1-{[5-(1H-pyrazolo[3,4-c]pyridin-5-yl)pyridin...)
Affinity DataIC50: 78nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16789BDBM16789(3-[(2S)-2-amino-3-[(5-{1H-pyrazolo[3,4-c]pyridin-5...)
Affinity DataIC50: 110nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16795BDBM16795(3-[(2S)-2-amino-3-phenylpropoxy]-5-[3-(furan-2-yl)...)
Affinity DataIC50: 274nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16797BDBM16797(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-phenyl-1H-py...)
Affinity DataIC50: 371nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16582BDBM16582(5-{5-[(2S)-2-amino-3-[3-(cyclohexylmethoxy)phenyl]...)
Affinity DataIC50: 3.00E+3nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed