Compile Data Set for Download or QSAR
Report error Found 61 of Enz. Inhib. data with enzyme = 'cAMP-dependent protein kinase catalytic subunit alpha' and Substrate = 'histone (type Vs)'
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 121nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2715(3-[(2R)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 900nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 900nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2702(3-[3-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...)
Affinity DataIC50: 1.10E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2710(3-[8-Amino-7,8,9,10-tetrahydro-6H-azepino[1,2-a]in...)
Affinity DataIC50: 2.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2704(3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 2.60E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3176([(4-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 2.70E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2700(3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]...)
Affinity DataIC50: 2.80E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
Affinity DataIC50: 2.90E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2711(3-(1,2,3,4-Tetrahydropyrazino[1,2-a]indol-10-yl)-4...)
Affinity DataIC50: 3.20E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2708(3-{2-amino-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4...)
Affinity DataIC50: 3.30E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2699(3-[2-(aminomethyl)-1H,2H,3H-benzo[b]pyrrolizin-9-y...)
Affinity DataIC50: 3.90E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2709(3-{3-amino-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4...)
Affinity DataIC50: 4.10E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2703(3-[3-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 4.50E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3177([(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 4.60E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2712(3-(1-methyl-1H-indol-3-yl)-4-{2-[(methylamino)meth...)
Affinity DataIC50: 4.80E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3178(3-(1-Methyl-3-indolyl)-4-[1-[3-(2-nitroguanidino)p...)
Affinity DataIC50: 4.90E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataIC50: 5.20E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataIC50: 5.20E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 7.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2606(3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H...)
Affinity DataIC50: 8.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2705(3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyr...)
Affinity DataIC50: 8.60E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3167(3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 8.90E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 9.30E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3170(3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
Affinity DataIC50: 1.04E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2607(3-(1,5-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50: 1.15E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2583(bis-indolylmaleimide deriv. 8a | 3,4-bis(1H-indol-...)
Affinity DataIC50: 1.18E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM3171(3-[1-[3-(Methylamino)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50: 1.19E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2714(3-[(2S)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 1.21E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3174([(2-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 1.21E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2706(3-[7-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 1.28E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2631(3-(1,4-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50: 1.30E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2610(3-(5-Methoxy-1-methyl-3-indolyl)-4-(1-methyl-3-ind...)
Affinity DataIC50: 1.40E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)
Affinity DataIC50: 1.42E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2620(3-(6-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-...)
Affinity DataIC50: 1.45E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2591(3,4-bis(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyr...)
Affinity DataIC50: 1.61E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50: 1.84E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)
Affinity DataIC50: 2.13E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2614(3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-5-nitro-1H-...)
Affinity DataIC50: 2.13E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2652(3-(1-methyl-1H-indol-3-yl)-4-(2-nitrophenyl)-2,5-d...)
Affinity DataIC50: 2.15E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM3163(3-[1-(2-hydroxyethyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50: 2.21E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2627(3-(7-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-...)
Affinity DataIC50: 2.30E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2697(3-[6,7,8,9-Tetrahydropyrido[1,2-a]indol-10-yl]-4-(...)
Affinity DataIC50: 2.30E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2701(3-[2-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 2.40E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 2.56E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2634(3-(1,2-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
Affinity DataIC50: 3.10E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
LigandPNGBDBM2707(3-[9-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 3.40E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM3173(trimethyl(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dio...)
Affinity DataIC50: 6.45E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2696(3-{1H,2H,3H-benzo[b]pyrrolizin-9-yl}-4-(1-methyl-1...)
Affinity DataIC50: 6.80E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2655(3-(2,5-dimethylphenyl)-4-(1-methyl-1H-indol-3-yl)-...)
Affinity DataIC50: 8.20E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
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