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TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1948(3-methyl-1-{2-[(4-{methyl[3-(propan-2-ylamino)pyri...)
Affinity DataAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataEC50:  961nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466688(CHEMBL4276678)
Affinity DataEC50:  172nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466689(CHEMBL4284250)
Affinity DataEC50:  1.74E+3nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466690(CHEMBL4293295)
Affinity DataEC50:  271nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataEC50:  98nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataEC50:  657nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466692(CHEMBL4286980)
Affinity DataEC50:  1.72E+3nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  8nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064007(6-Chloro-2-((S)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against E233V mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064007(6-Chloro-2-((S)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against wild type HIV-1 reverse transcriptase (WT-RT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064007(6-Chloro-2-((S)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against P236L mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064009(6-Chloro-2-(1-furo[2,3-c]pyridin-5-yl-ethylsulfany...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against P236L mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064009(6-Chloro-2-(1-furo[2,3-c]pyridin-5-yl-ethylsulfany...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against wild type HIV-1 reverse transcriptase (WT-RT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064008(6-Chloro-2-((R)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against P236L mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064007(6-Chloro-2-((S)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against L100I mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064009(6-Chloro-2-(1-furo[2,3-c]pyridin-5-yl-ethylsulfany...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against L100I mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064009(6-Chloro-2-(1-furo[2,3-c]pyridin-5-yl-ethylsulfany...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against E233V mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064009(6-Chloro-2-(1-furo[2,3-c]pyridin-5-yl-ethylsulfany...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against Y188H mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081628(N-(2-{4-[(3-Ethyl-pyridin-2-yl)-methyl-amino]-pipe...)
Affinity DataIC50: 61nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064007(6-Chloro-2-((S)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against Y188H mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064008(6-Chloro-2-((R)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 85nMAssay Description:Inhibitory activity against wild type HIV-1 reverse transcriptase (WT-RT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1954(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 90nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081631(N-(2-{4-[Ethyl-(3-ethyl-pyridin-2-yl)-amino]-piper...)
Affinity DataIC50: 98nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1317(3-{[(4,7-dichloro-1,3-benzoxazol-2-yl)methyl]amino...)
Affinity DataIC50: 110nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 112nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50150998(2-[(4-methoxyphenoxycarbonyl)({4-[2-(5-methyl-2-ph...)
Affinity DataIC50: 120nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1966(1-[(5-Methylsulfonaminoindol-2-yl)carbonyl]-4-[N-e...)
Affinity DataIC50: 130nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081622(N-(2-{4-[(3-Ethyl-pyridin-2-yl)-propyl-amino]-pipe...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1967(1-[[5-[[(4-Methyl-1-piperazinyl)carbonyl]amino]ind...)
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1969(N-{2-[(4-{ethyl[3-(propan-2-ylamino)pyridin-2-yl]a...)
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081624(N-(2-{4-[(3-Methoxymethyl-pyridin-2-yl)-methyl-ami...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081625(N-(2-{4-[Ethyl-(3-methoxymethyl-pyridin-2-yl)-amin...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1964(N-{2-[(4-{[3-(ethylamino)pyridin-2-yl](propyl)amin...)
Affinity DataIC50: 150nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1955(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 160nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1950({2-[(4-{methyl[3-(propan-2-ylamino)pyridin-2-yl]am...)
Affinity DataIC50: 170nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM1956(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Reverse transcriptase (P236L) using poly(rA)600:oligo(dT)10 as template primer.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064007(6-Chloro-2-((S)-1-furo[2,3-c]pyridin-5-yl-ethylsul...)
Affinity DataIC50: 179nMAssay Description:Inhibitory activity against Y181C mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1948(3-methyl-1-{2-[(4-{methyl[3-(propan-2-ylamino)pyri...)
Affinity DataIC50: 180nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1969(N-{2-[(4-{ethyl[3-(propan-2-ylamino)pyridin-2-yl]a...)
Affinity DataIC50: 180nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2661(4-methyl-N-{2-[(4-{[3-(propan-2-ylamino)pyridin-2-...)
Affinity DataIC50: 190nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1956(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 200nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2668(1-[[5-[[(4-Methyl-1-piperazinyl)carbonyl]amino]ind...)
Affinity DataIC50: 210nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1954(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 210nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081631(N-(2-{4-[Ethyl-(3-ethyl-pyridin-2-yl)-amino]-piper...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Reverse transcriptase (P236L) using poly(rA)600:oligo(dT)10 as template primer.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2659(N-{2-[(4-{[3-(tert-butylamino)pyridin-2-yl](ethyl)...)
Affinity DataIC50: 220nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1945(2-N-[1-(1H-indol-2-ylcarbonyl)piperidin-4-yl]-2-N-...)
Affinity DataIC50: 230nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1958(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 230nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1957(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 240nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1968(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 240nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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