Report error Found 107 with Last Name = 'benkovic' and Initial = 'sj'
Affinity DataKd: 1.40nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46A Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Thermodynamic dissociation constant of compound for wild type Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Thermodynamic dissociation constant of compound for wild type Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 243nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46A Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46S Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46N Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46N Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46N Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 300nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKd: 3.20nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 2.30nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKoff: 3.60E+7s-1Assay Description:Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKon: 25M-1s-1Assay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 9.5More data for this Ligand-Target Pair
Affinity DataKd: 490nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKd: 300nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 810nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 4.80E+3nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 4.40E+3nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 6.20E+3nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKon: 12M-1s-1Assay Description:Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKoff: 1.20E+7s-1Assay Description:Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKoff: 1.10E+7s-1Assay Description:Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 340nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 210nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 6.60E+3nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 140nMpH: 8.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKd: 0.0960nMpH: 8.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 9.5More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 3.90E+3nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKon: 26M-1s-1Assay Description:Dissociation constant at Val-31(Kon)of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 31nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 9.5More data for this Ligand-Target Pair
Affinity DataKd: 0.0230nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 240nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKoff: 6.80E+6s-1Assay Description:Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 400nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKoff: 1.50E+5s-1Assay Description:Association constant at Val-31(Kon) of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 220nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 300nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 60nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 380nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKon: 35M-1s-1Assay Description:Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 84nMpH: 8.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKon: 26M-1s-1Assay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
Pennsylvania State University
Curated by ChEMBL
Pennsylvania State University
Curated by ChEMBL
Affinity DataKd: 0.25nMAssay Description:Thermodynamic dissociation constant (KD) was measured upon binding to GAR TFase in miceMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Pennsylvania State University
Curated by ChEMBL
The Pennsylvania State University
Curated by ChEMBL
Affinity DataKd: 20nMAssay Description:Binding affinity towards AICAR formyltransferaseMore data for this Ligand-Target Pair
Affinity DataKd: 2.08E+4nMAssay Description:Binding affinity to Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase in presence of AMPMore data for this Ligand-Target Pair
