Compile Data Set for Download or QSAR
Report error Found 45 with Last Name = 'chen' and Initial = 'sf'
TargetAdenosine receptor A2a(Human)
University of Rhode Island

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataEC50:  4.00E+4nMAssay Description:Effective concentration required for cyclic AMP dependent inhibition of blood platelet aggregation for A2 receptor stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223090(3-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50: 14nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50095259(N-(3-ethynylphenyl)-6,7-dimethoxyquinazolin-4-amin...)
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 39nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223084(N-(3-chloro-4-fluorophenyl)-6-(3-morpholinoprop-1-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223082(N-(3-chloro-4-fluorophenyl)-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 89nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223095(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50: 95nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223092(5-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50: 114nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223085(N-(3-chloro-4-fluorophenyl)-6-ethynylquinazolin-4-...)
Affinity DataIC50: 127nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223093(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50: 152nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223088(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50: 186nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223086(4-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-2-...)
Affinity DataIC50: 206nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223094(N-(3-chloro-4-fluorophenyl)-6-(2-phenylethynyl)qui...)
Affinity DataIC50: 331nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223091(4-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)but...)
Affinity DataIC50: 402nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223087(6,7-dimethoxy-N-(3-(2-phenylethynyl)phenyl)quinazo...)
Affinity DataIC50: 921nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50: 950nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167309(1-Benzo[b]thiophen-2-ylmethyl-7-bromo-1H-indole-2,...)
Affinity DataIC50: 980nMAssay Description:In vitro inhibitory concentration SARS coronavirus main protease (SARS CoV 3C-like protease) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
National Chiayi University

Curated by ChEMBL
LigandPNGBDBM50418088(7-ETHYL-10-HYDROXY-CAMPTOTHECIN)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against Chymotrypsin (serine protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223089(5-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)pen...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223096(N-(3-chloro-4-fluorophenyl)-6-(2-(thiophen-2-yl)et...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223083(3-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)pro...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167306(1-Benzo[b]thiophen-2-ylmethyl-7-nitro-1H-indole-2,...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167311(1-Benzo[b]thiophen-2-ylmethyl-5-fluoro-1H-indole-2...)
Affinity DataIC50: 4.82E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
National Chiayi University

Curated by ChEMBL
LigandPNGBDBM50557284(CHEMBL4789468)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167314(1-(3,5-Dimethyl-isoxazol-4-ylmethyl)-2,3-dioxo-2,3...)
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167317(1-(2-Chloro-4-fluoro-benzyl)-5-iodo-1H-indole-2,3-...)
Affinity DataIC50: 9.40E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167309(1-Benzo[b]thiophen-2-ylmethyl-7-bromo-1H-indole-2,...)
Affinity DataIC50: 1.04E+4nMAssay Description:In vitro inhibitory concentration against Chymotrypsin (serine protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167312(1-Benzo[b]thiophen-2-ylmethyl-4-chloro-1H-indole-2...)
Affinity DataIC50: 1.12E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167308(5-(5-Iodo-2,3-dioxo-2,3-dihydro-indol-1-ylmethyl)-...)
Affinity DataIC50: 1.26E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167313(1-Benzo[b]thiophen-2-ylmethyl-1H-indole-2,3-dione ...)
Affinity DataIC50: 1.31E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167316(1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-5-iodo...)
Affinity DataIC50: 1.35E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease) at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167315(5-Iodo-1-[5-(piperidine-1-carbonyl)-thiophen-2-ylm...)
Affinity DataIC50: 1.75E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167310(1-((E)-3-Benzo[b]thiophen-2-yl-allyl)-5-iodo-1H-in...)
Affinity DataIC50: 2.35E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
National Chiayi University

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 6.29E+4nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM22925(Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM28393((2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | CHEM...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404651(CHEMBL1555103)
Affinity DataKi:  80nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50404652(CHEMBL2114367)
Affinity DataKi:  122nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50034908((2R,3S)-3-(6-Amino-purin-9-yl)-nonan-2-ol | 3-(6-A...)
Affinity DataKi:  500nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50034908((2R,3S)-3-(6-Amino-purin-9-yl)-nonan-2-ol | 3-(6-A...)
Affinity DataKi:  500nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368778(CHEMBL610668)
Affinity DataKi:  1.41E+6nMAssay Description:Tested for inhibition against human plasma adenosine deaminase (ADA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataKi:  2.18E+6nMAssay Description:Tested for binding constant against adenosine deaminase (ADA2) in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed