Compile Data Set for Download or QSAR
Report error Found 616 with Last Name = 'chene' and Initial = 'p'
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50175688((4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)p...)
Affinity DataEC50:  3nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139468(US8889672, 317-054-001)
Affinity DataEC50:  10nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139466(US8889672, 317-094-001)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139469(US8889672, 317-052-004)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139465(US8889672, 317-080-001)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139472(US8889672, 252-036-001)
Affinity DataEC50:  2nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139464(US8889672, 194-074-007 | US8889672, PKCzI-diMeO)
Affinity DataEC50:  3nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Penn State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM139467(US8889672, 268-020-002)
Affinity DataEC50:  2nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50535722(CHEMBL4468725)
Affinity DataKd:  25nMAssay Description:Binding affinity to Avi-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21 (DE3) by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398838(CHEMBL2177545)
Affinity DataEC50:  590nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398839(CHEMBL2177544)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398818(CHEMBL2177540)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398819(CHEMBL2177539)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398820(CHEMBL2177538)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398821(CHEMBL2177537)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398830(CHEMBL2177516)
Affinity DataEC50:  595nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398832(CHEMBL2177518)
Affinity DataEC50:  162nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398835(CHEMBL2177521)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398837(CHEMBL2177530)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398840(CHEMBL2177529)
Affinity DataEC50:  9.66E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398841(CHEMBL2177528)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398842(CHEMBL2177527)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398843(CHEMBL2177524)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398844(CHEMBL2177523)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398845(CHEMBL2177522)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398846(CHEMBL2177532)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398847(CHEMBL2177535)
Affinity DataEC50:  343nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398848(CHEMBL2178156)
Affinity DataEC50:  4.19E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398849(CHEMBL2177553)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398850(CHEMBL2177552)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398851(CHEMBL2177546)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398838(CHEMBL2177545)
Affinity DataEC50:  654nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398839(CHEMBL2177544)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataEC50:  562nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398816(CHEMBL2177542)
Affinity DataEC50:  5.13E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398817(CHEMBL2177541)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398818(CHEMBL2177540)
Affinity DataEC50:  7.66E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398819(CHEMBL2177539)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398820(CHEMBL2177538)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398821(CHEMBL2177537)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398830(CHEMBL2177516)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398832(CHEMBL2177518)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398835(CHEMBL2177521)
Affinity DataEC50:  3.25E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398837(CHEMBL2177530)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398840(CHEMBL2177529)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398841(CHEMBL2177528)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398842(CHEMBL2177527)
Affinity DataEC50:  3.46E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398843(CHEMBL2177524)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398844(CHEMBL2177523)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 616 total ) | Next | Last >>
Jump to: