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TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50099009(CHEMBL3350086 | BDBM50204612 | (3S,4S,5R)-2-Aminom...)
Affinity DataIC50: 53nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50099009(CHEMBL3350086 | BDBM50204612 | (3S,4S,5R)-2-Aminom...)
Affinity DataIC50: 670nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 750nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 1.00E+3nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204611(CHEMBL1289018 | D-15)
Affinity DataIC50: 9.50E+3nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204610(CHEMBL3908900)
Affinity DataIC50: 1.06E+4nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204609(CHEMBL3985941)
Affinity DataIC50: 1.40E+4nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204613(CHEMBL3929052)
Affinity DataIC50: 2.21E+4nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204610(CHEMBL3908900)
Affinity DataIC50: 3.42E+4nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204609(CHEMBL3985941)
Affinity DataIC50: 2.66E+5nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
National Yang Ming Chiao Tung University

Curated by ChEMBL
LigandPNGBDBM50375511(CHEMBL406973)
Affinity DataKi:  1.40E+3nMAssay Description:Competitive inhibition of recombinant human lysosomal alpha-glucosidase assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Human)
National Yang Ming Chiao Tung University

Curated by ChEMBL
LigandPNGBDBM50375510(CHEMBL405957)
Affinity DataKi:  6.40E+3nMAssay Description:Competitive inhibition of recombinant human lysosomal alpha-glucosidase assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Human)
National Yang Ming Chiao Tung University

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataKi:  1.15E+5nMAssay Description:Competitive inhibition of recombinant human lysosomal alpha-glucosidase assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed